5282-87-1

Basic information

• Product Name: Dansyl-MethylaMine
• Synonyms: Dansyl-MethylaMine
• CAS NO: 5282-87-1
• Molecular Formula: C13H16N2O2S
• Molecular Weight: 264.34334
• Product Categories: Amines, Aromatics, Fluorescent Labels & Indicators, Sulfur & Selenium Compounds
• Mol File: 5282-87-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
• Solubility: Chloroform, Ethyl Acetate
• CAS DataBase Reference: Dansyl-MethylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: Dansyl-MethylaMine(5282-87-1)
• EPA Substance Registry System: Dansyl-MethylaMine(5282-87-1)

Safety Data

• Hazardous Substances Data: 5282-87-1(Hazardous Substances Data)

Usage

Uses

Dansyl-methylamine is fluorescently labelled Methanamine Hydrochloride (M258875) which is used in the synthesis of betaine-homocysteine S-methyltransferase. It is also used in the synthesis of novel oxazinones as polymerase inhibitors.

Upstream product

• 605-65-2 5-(dimethylamino)naphth-1-ylsulfonyl chloride 
• 74-89-5 methylamine 
• 593-51-1 methylamine hydrochloride 

Relevant articles and documents

To D or not to D?: On estimating the microenvironment polarity of biomolecular cavities

Knowledge of the local polarity of specific cavities in biopolymers can facilitate the design of selective low MW ligands that impact the structure and function of macromolecules. The most common tools for interrogating local polarity are fluorescent probes that are sensitive to their microenvironment. Researchers often evaluate and express this local polarity using dielectric constants, a parameter that reflects an inherent bulk property. A more appropriate expression should take into account solvent-solute interactions at the molecular level. Reevaluation of commonly used fluorophores illustrates the improved correlation between observed Stokes shift changes and ET(30) values as compared to the corresponding dielectric constants. The Royal Society of Chemistry.