52827-01-7

Basic information

• Product Name: [(4-methoxyphenyl)(nitroso)amino]acetic acid
• CAS NO: 52827-01-7
• Molecular Formula: C₉H₁₀N₂O₄
• Molecular Weight: 210.1867
• Mol File: 52827-01-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 462.5°C at 760 mmHg
• Flash Point: 233.5°C
• Density: 1.29g/cm³
• Vapor Pressure: 2.37E-09mmHg at 25°C
• Refractive Index: 1.558
• CAS DataBase Reference: [(4-methoxyphenyl)(nitroso)amino]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [(4-methoxyphenyl)(nitroso)amino]acetic acid(52827-01-7)
• EPA Substance Registry System: [(4-methoxyphenyl)(nitroso)amino]acetic acid(52827-01-7)

Safety Data

• Hazardous Substances Data: 52827-01-7(Hazardous Substances Data)

Usage

General Description

[(4-methoxyphenyl)(nitroso)amino]acetic acid is a chemical compound with the molecular formula C9H10N2O5. It is a derivative of the amino acid glycine, and is primarily used in research and laboratory settings. The compound contains a nitroso group, which is a functional group consisting of a nitrogen atom bonded to an oxygen atom, and a 4-methoxyphenyl group, which is a benzene ring with a methoxy (CH3O) substituent attached to the fourth carbon. [(4-methoxyphenyl)(nitroso)amino]acetic acid has potential applications in medicinal chemistry and drug development, and its unique structure makes it an interesting subject for further investigation in the field of organic chemistry.

Upstream product

• 50845-77-7 N-(4-methoxy)phenylglycine ethyl ester 
• 104-94-9 4-methoxy-aniline 
• 22094-69-5 N-(4-methoxyphenyl)glycine 

Relevant articles and documents

Novel sydnone derivatives carrying azidomethyl-1,2, 4-oxadiazole unit and their 1,3-dipolar cycloadditions

A series of 1,2,4-oxadiazolymethyl sydnones carrying azido group were synthesized and subjected to react with a variety of alkenic and acetylenic dipolarophilic reagents; N-phenyl maleimide, phenyl vinyl sulfone, and phenyl propiolic acid. All the new products are identified by spectral/physical data including high-resolution mass measurements and X-ray diffraction data.

One-pot synthesis of 1,4-disubstituted pyrazoles from arylglycines via copper-catalyzed sydnone-alkyne cycloaddition reaction

A robust method for constructing 1,4-pyrazoles from arylglycines was developed using the copper-catalyzed sydnone-alkyne cycloaddition reaction. The procedure offers a straightforward and general route to the pyrazole heterocycle through a three-step one-pot procedure.

Regioselective reaction: Synthesis, characterization and pharmacological activity of some new Mannich and Schiff bases containing sydnone

A novel series of 1-substituted aminomethyl-3-[1-(4-isobutylphenyl)ethyl]- 4-(3-aryl-4-sydnonylidene) amino-1,2,4-triazol-5-thiones (9), was prepared from the 3-[1-(4-isobutylphenyl)ethyl]-4-(3-aryl-4-sydnonylidene) amino 5-mercapto-1,2,4-triazoles (8) by aminomethylation with formaldehyde and secondary amine. The structures of Schiff bases (8) and Mannich bases (9) were characterized on the basis of IR, NMR, mass spectra1 data and elemental analysis. The newly synthesized compounds were screened for their anti-inflammatory and analgesic activities. Mannich bases (9) carrying piperidine and morpholine residues showed promising anti-inflammatory and analgesic activity.