[(4-Methoxyphenyl)(nitroso)amino]acetic acid

Base Information

Chemical Name:[(4-Methoxyphenyl)(nitroso)amino]acetic acid
CAS No.:52827-01-7
Molecular Formula:C9H10N2O4
Molecular Weight:210.189
Hs Code.:
NSC Number:121384
DSSTox Substance ID:DTXSID30298195
Nikkaji Number:J2.265.371G
Wikidata:Q82039849
Pharos Ligand ID:3XUXFXMUQC19
ChEMBL ID:CHEMBL1318137

Synonyms:52827-01-7;NSC121384;NSC-121384;[(4-methoxyphenyl)(nitroso)amino]acetic acid;N-(4-Methoxyphenyl)-N-nitrosoglycine;NCIStruc1_001952;NCIStruc2_000653;SCHEMBL6172326;CHEMBL1318137;DTXSID30298195;MBYDBHKSYFMVSP-UHFFFAOYSA-N;CCG-37585;NCGC00014235;NCI121384;N-nitroso-N-(4-methoxyphenyl)glycine;NCGC00014235-02;NCGC00097344-01;NCI60_000501;(1-(4-methoxyphenyl)-2-oxohydrazino)acetic acid

Suppliers and Price of [(4-Methoxyphenyl)(nitroso)amino]acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of [(4-Methoxyphenyl)(nitroso)amino]acetic acid

Chemical Property:

Vapor Pressure:2.37E-09mmHg at 25°C
Boiling Point:462.5°Cat760mmHg
Flash Point:233.5°C
Density:1.29g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:210.06405680
Heavy Atom Count:15
Complexity:226

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N(CC(=O)O)N=O

Technology Process of [(4-Methoxyphenyl)(nitroso)amino]acetic acid

There total 4 articles about [(4-Methoxyphenyl)(nitroso)amino]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 22094-69-5
N-(4-methoxyphenyl)glycine

: 52827-01-7
2-((4-methoxyphenyl)(nitroso)amino)acetic acid

Guidance literature:: With silica gel; periodic acid; sodium nitrite; In dichloromethane; at 0 - 5 ℃; for 1.9h;
DOI:10.3987/COM-05-10574

Reference yield:

: 104-94-9
4-methoxy-aniline

: 52827-01-7
2-((4-methoxyphenyl)(nitroso)amino)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium acetate / ethanol / Reflux

2.1: lithium hydroxide / tetrahydrofuran; water / 2 h / 2 °C

2.2: 20 °C / pH 3 - 4

3.1: sodium nitrite / water / 0.33 h / 0 °C

With sodium acetate; lithium hydroxide; sodium nitrite; In tetrahydrofuran; ethanol; water;
DOI:10.1021/jo201605v

Reference yield:

: 50845-77-7
N-(4-methoxy)phenylglycine ethyl ester

: 52827-01-7
2-((4-methoxyphenyl)(nitroso)amino)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hydroxide / tetrahydrofuran; water / 2 h / 2 °C

1.2: 20 °C / pH 3 - 4

2.1: sodium nitrite / water / 0.33 h / 0 °C

With lithium hydroxide; sodium nitrite; In tetrahydrofuran; water;
DOI:10.1021/jo201605v