52841-95-9Relevant academic research and scientific papers
CATHEPSIN CYSTEINE PROTEASE INHIBITORS
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Page/Page column 86, (2015/04/28)
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
CATHEPSIN CYSTEINE PROTEASE INHIBITORS
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Page/Page column 73, (2015/04/28)
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
1, 2-Disubstituted cyclohexane derived tripeptide aldehydes as novel selective thrombin inhibitors
Harmat, Nicholas J.S.,Di Bugno, Cristina,Criscuoli,Giorgi, Raffaello,Lippi, Annalisa,Martinelli, Adriano,Monti, Susanna,Subissi
, p. 1249 - 1254 (2007/10/03)
A series of tripeptide arginine aldehydes was synthesized by replacement of proline with 1,2-disubstituted cyclohexane derivatives in the sequence of D-MePhe-Pro-Arg-H. Based on molecular modeling, further modification of the D-MePhe residue resulted in a potent and selective thrombin inhibitor.
Circular Dichroism Spectra and Molecular Geometry of Six-Membered Ring Anhydrides and Imides
Polonski, Tadeusz
, p. 639 - 648 (2007/10/02)
Several six-membered ring anhydrides and imides of known absolute configuration have been synthesized and their c.d. spectra measured.It has been established that the shape of the c.d. curves of anhydrides is generally similar to those of the correspondin
