528521-80-4Relevant academic research and scientific papers
Synthesis of spiro diphosphines and their application in asymmetric hydrogenation of ketones
Xie, Jian-Hua,Wang, Li-Xin,Fu, Yu,Zhu, Shuo-Fei,Fan, Bao-Min,Duan, Hai-Feng,Zhou, Qi-Lin
, p. 4404 - 4405 (2007/10/03)
Synthesis of chiral diphosphine ligands containing a spiro scaffold was described. The ruthenium complexes of these spiro ligands were found to have extremely high activities (S/C up to 100000) and enantioselectivities (ee up to 99.5%) in the asymmetric hydrogenation of aromatic, heteroaromatic, and α,β-unsaturated ketones. Copyright
