528584-68-1Relevant academic research and scientific papers
TEMPO-mediated anodic oxidation of methyl glycosides and 1-methyl and 1-azido disaccharides
Schaemann, Matthias,Schaefer, Hans J.
, p. 351 - 358 (2007/10/03)
Methyl glycosides of L-sorbopyranoside, D-fructopyranoside, D-glucosaminopyranoside, 2,3-dehydro-2,3-dideoxyglucopyranoside, cellobiose, lactose, and maltose and the 1-azido derivatives of glucose, cellobiose, lactose, and maltose have been converted into the corresponding uronic acids in moderate to excellent yields by TEMPO-mediated anodic oxidation. The anode proves to be an advantageous alternative to other cooxidants in TEMPO+ oxidations of carbohydrates and is compatible with N-acylamino and azido groups and with double bonds. The electrolyte, a carbonate buffer, can easily be removed with a cation-exchange resin, a facile scale-up by increasing the electrode area is possible. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
