528588-37-6

Upstream product

• 45214-91-3 (2S)-2-[(tert-butoxy)carbonylamino]-4-(methoxycarbonyl)butanoic acid 
• 24277-39-2 N-tert-butoxycarbonyl glutamic acid tert-butyl ester 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 24277-38-1 (S)-(-)-1-tert-butyl-5-methyl-<(2-tert-butoxycarbonyl)amino>pentanedioate 

Downstream Products

• 528588-45-6 4-(4-bromo-benzyl)-2-tert-butoxycarbonylamino-5-(toluene-4-sulfonyloxy)-pentanoic acid tert-butyl ester 
• 528588-41-2 5-(4-bromo-phenyl)-2-tert-butoxycarbonylamino-4-hydroxymethyl-pentanoic acid tert-butyl ester 

Relevant academic research and scientific papers

Diagnosis and treatment radioactive glutamine derivative and method for preparing same

The invention discloses a diagnosis and treatment radioactive glutamine derivative and a method for preparing the same, belongs to the field of glutamine derivative preparation, and relates to novel glutamine derivatives suitable to be labeled by F,

Efficient and stereoselective synthesis of novel cis-4-substituted proline analogues

A series of novel cis-4-substituted proline analogues were designed and synthesized. Highly stereoselective alkylations at the γ-position of glutamic ester 2 were achieved, followed by reduction, mesylation, and cyclization to afford the title compounds 1 in good yields and high diastereoselectivity.