528893-97-2

Upstream product

• 99-34-3 3,5-dinitrobenzoic acid 
• 1620809-34-8 ethyl 3-azido-5-iodobenzoate 
• 1620809-38-2 (3-ethoxycarbonyl-5-iodo)phenylboronic acid pinacol ester 
• 58313-23-8 3-iodobenzoic acid methyl ester 
• 90390-46-8 (3-amino-5-nitrophenyl)methanol 
• 219589-42-1 3-iodo-5-nitrobenzyl alcohol 
• 71022-43-0 3,5-dinitrobenzyl alcohol 
• 368435-46-5 3-amino-5-iodobenzyl alcohol 

Downstream Products

• 528893-95-0 (3-azido-5-iodo)benzyl bromide 
• 1157852-34-0 3-azido-5-iodobenzylmethanesulfonate 
• 1157852-35-1 1-azido-3-(azidomethyl)-5-iodobenzene 
• 1157852-36-2 2-[3-azido-5-(azidomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1620809-46-2 3-azido-5-(azidomethyl)phenol 
• 849607-21-2 3-azido-5-ethynylbenzyl alcohol 
• 849607-22-3 3-azido-5-ethynylbenzyl bromide 

Relevant academic research and scientific papers

Synthesis of diverse 3-azido-5-(azidomethyl)benzene derivatives via formal C-H azidation and functional group-selective transformations

3-Azido-5-(azidomethyl)benzene derivatives are useful compounds for preparing diverse bistriazole compounds and photoaffinity probes for target identification of bioactive compounds. To more easily synthesize a diverse range of diazido compounds, a facile

Formal C-H-azidation-based shortcut to diazido building blocks for the versatile preparation of photoaffinity labeling probes

Short synthetic routes to diazido building blocks with different connectable groups were established on the basis of the sequential iridium-catalyzed C-H borylation and copper-catalyzed azidation of 1,3-disubstituted benzenes, followed by diverse azido-fr

Synthesis of polynorbornene with pendant moiety bearing azide and terminal alkyne groups

A powerful approach to the synthesis of an unprecedented polynorbornene with pendant moiety bearing azide and terminal alkyne groups is developed. Two key intermediates, namely, 3-azido-5-(2-(trimethylsilyl)ethynyl) benzyl alcohol and 4-(4-aza-tricyclo [5.2.1.02.6]dec-8-en-4-yl) benzoic acid, were optimally synthesized for convergent synthesis of the corresponding monomer.

[(125)I]-N-[(3-azido-5-iodo)benzyl]dantrolene and [(125)I]-N-[[3-iodo-5-(3-trifluoromethyl-3H-diazirin-3-yl)]benzyl]dantrolene: photoaffinity probes specific for the physiological Ca(2+) release from sarcoplasmic reticulum of skeletal muscle.

In order to capture and identify key molecules that regulate the release of Ca(2+) from the sarcoplasmic reticulum (SR) of skeletal muscle, we designed specific photoaffinity probes based on the structural modification of dantrolene. Thus, GIF-0082 and GIF-0276 possessing azido- and trifluoromethyldiazirinyl-benzyl groups, respectively, at the hydantoin moiety were found to have a highly selective inhibitory effect on physiological Ca(2+) release (PCR) without affecting Ca(2+)-induced Ca(2+) release (CICR). Successful realization of the sharp discrimination between PCR and CICR has led to the creation of [(125)I]GIF-0082 and [(125)I]GIF-0276, which were synthesized by substituting a stannyl group with (125)I in the corresponding phenylstannane precursors.