52893-00-2

Upstream product

• 61-82-5 3⁽⁵⁾-amino-1,2,4-triazole 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 4866-62-0 6-carboxy-7-hydroxy-1,2,4-triazolo<1,5-a>pyrimidine 

Relevant academic research and scientific papers

X-Ray Analysis of 6-Ethoxycarbonyl-4-ethylpyrazolopyrimidin-7(4H)-one and 6-Ethoxycarbonyl-4-ethyl-1,2,4-triazolopyrimidin-7(4H)-one

The product obtained by treating 6-ethoxycarbonyl-7-hydroxypyrazolopyrimidine (2a) with ethyl iodide is shown by X-ray analysis to be 6-ethoxycarbonyl-4-ethylpyrazolopyrimidin-7(4H)-one (3a).When 3-amino-1,2,4-triazole (5a) was cyclised with diethyl ethoxymethylenemalonate the product was shown to have the structure (2b), rather than (6), by an X-ray analysis of its N-ethyl derivative, 6-ethoxycarbonyl-4-ethyl-1,2,4-triazolopyrimidin-7(4H)-one (3d).Carbon-13 chemical shift values in the above and related compounds have been assigned.

Penicillins

A class of α-(heterocyclic carbonylamino) penicillins in which the heterocyclic group of the acyl moiety is a fused bicyclic ring having a nitrogen atom at the bridge position, shows good antibacterial activity.