529-27-1

Basic information

• Product Name: o-tolylhydrazine
• Synonyms: 1-(2-Methylphenyl)hydrazine;Hydrazine, (2-Methylphenyl)-
• CAS NO: 529-27-1
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.1677
• EINECS: 208-455-9
• Mol File: 529-27-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 163-165 °C
• Boiling Point: 227.7°Cat760mmHg
• Flash Point: 104.1°C
• Appearance: /
• Density: 1.087g/cm³
• Vapor Pressure: 0.0766mmHg at 25°C
• Refractive Index: 1.622
• PKA: 5.33±0.10(Predicted)
• CAS DataBase Reference: o-tolylhydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: o-tolylhydrazine(529-27-1)
• EPA Substance Registry System: o-tolylhydrazine(529-27-1)

Safety Data

• Hazardous Substances Data: 529-27-1(Hazardous Substances Data)

Usage

General Description

O-tolylhydrazine is a chemical compound with the formula C7H10N2. It is a colorless to pale yellow liquid with a mild odor, and it is primarily used in the production of dyes and other organic compounds. O-tolylhydrazine is a common reagent in organic chemistry, particularly in the synthesis of pharmaceuticals and agricultural chemicals. It is also used in the production of rubber and plastics. O-tolylhydrazine is a hazardous material, with potential health effects including skin and eye irritation, and it should be handled and stored with appropriate safety precautions.

InChI:InChI=1/C7H10N2/c1-6-4-2-3-5-7(6)9-8/h2-5,9H,8H2,1H3

Upstream product

• 2028-34-4 o-toluene-diazonium chloride 
• 95-49-8 2-methylchlorobenzene 
• 615-37-2 ortho-methylphenyl iodide 
• 95-53-4 o-toluidine 
• 7647-01-0 hydrogenchloride 
• 17333-74-3 2-methylbenzene diazonium 

Downstream Products

• 40887-62-5 ethyl 2-o-tolylhydrazinecarboxylate 
• 854715-10-9 cyclohexanone-o-tolylhydrazone 
• 6304-59-2 formic acid-(N'-o-tolyl-hydrazide) 
• 6463-30-5 1-o-tolyl-4,5-dihydro-1H-pyrazol-3-ylamine 
• 106166-33-0 5-nitro-2-o-tolyl-2H-benzotriazole 
• 6243-73-8 acetone-o-tolylhydrazone 

Relevant articles and documents

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Preparation method of 2-methyl phenylhydrazine sulfate

The invention relates to a preparation method of 2-methyl phenylhydrazine sulfate. The preparation method comprises the following steps: diazotization, reduction, purification and salt formation. In the diazotization and reduction steps, reaction liquid is kept with high acidity by means of concentrated hydrochloric acid, so that the reaction is smoothly and fully carried out. In the reduction step, zinc powder-concentrated hydrochloric acid is taken as a reducing agent to replace sodium thiosulfate, sodium hydrogen sulfite, stannous chloride-hydrochloric and the like, the reducing property isgood, the yield is high, the reaction time is shortened, impurities such as zinc hydroxide generated by the reaction are conveniently removed, and the product is few in impurity and high in purity. In the salt formation step, acetone is used to wash, so that the purity of the product is improved, and the appearance of the product is ensured. According to the preparation method, the process is stable and reliable, the operation is easy, the product purity is high (the content of the product detected by high performance liquid chromatography is greater than or equal to 99.1%), the yield is greater than or equal to 42%, and the demand on 2-methyl phenylhydrazine sulfate in the market is fully met.

Preparation method of 2-methyl phenylhydrazine hydrochloride

The invention relates to a preparation method of 2-methyl phenylhydrazine hydrochloride. The preparation method comprises the following steps: diazotization, reduction, purification and salt formation. In the diazotization and reduction steps, reaction liquid is kept with high acidity by means of concentrated hydrochloric acid, so that the reaction is smoothly and fully carried out. In the reduction step, zinc powder-concentrated hydrochloric acid is taken as a reducing agent to replace sodium thiosulfate, sodium hydrogen sulfite, stannous chloride-hydrochloric and the like, the reducing property is good, the yield is high, the reaction time is shortened, impurities such as zinc hydroxide generated by the reaction are conveniently removed, and the product is few in impurity and high in purity. In the salt formation step, acetone is used to wash, so that the purity of the product is improved, and the appearance of the product is ensured. According to the preparation method, the processis stable and reliable, the operation is easy, the product purity is high (the content of the product detected by high performance liquid chromatography is greater than or equal to 99%), the yield isgreater than or equal to 39%, and the demand on 2-methyl phenylhydrazine hydrochloride in the market is fully met.