529-70-4

Usage

Type

Chemical compound

Classification

Coumarin derivative

Natural Occurrence

Found in various plant sources

Anti-inflammatory

Inhibits pro-inflammatory mediators

Antioxidant

Reduces oxidative stress in the body

Anti-cancer

Induces apoptosis and inhibits cancer cell growth

Health conditions

Shows promise for various health conditions

Pharmacological applications

Of interest to researchers for its potential applications

Research Focus

Investigated for its potential in cancer treatment and other health-related areas

InChI:InChI=1/C14H16O4/c1-8(15)12-10(16)7-11-9(13(12)17-4)5-6-14(2,3)18-11/h5-7,16H,1-4H3

Upstream product

• 27364-64-3 1-[4,6-dihydroxy-2-methoxy-3-(3-methylbut-2-enyl)-phenyl]ethanone 
• 27364-68-7 6-Acetyl-3,4-dihydro-7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran 
• 82538-75-8 2-hydroxy-3-iodo-4-O-(1,1-dimethylpropargyl)-6-methoxy-acetophenone 
• 171021-70-8 6-acetyl-5-methoxy-2,2-dimethyl-7-tosyloxy-2H-chromene 
• 541-47-9 3-Methylbutenoic acid 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 124360-56-1 6-acetyl-5,7-dihydroxy-2,2-dimethyl-4-chromanone 
• 124360-57-2 6-acetyl-5-hydroxy-2,2-dimethyl-7-tosyloxy-4-chromanone 
• 124360-58-3 6-acetyl-5-methoxy-2,2-dimethyl-7-tosyloxy-4-chromanone 
• 115-18-4 2-methyl-3-buten-2-ol 
• 74047-32-8 2,4-dihydroxy-3-iodo-6-methoxyphenyl methyl ketone 
• 78-79-5 isoprene 
• 3602-54-8 4,6-dihydroxy-2-methoxyacetophenone 
• 82538-76-9 2,4-dihydroxy-5-prenyl-3-iodo-6-methoxy-acetophenone 

Downstream Products

• 65463-74-3 oaxacacin 
• 27364-68-7 6-Acetyl-3,4-dihydro-7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran 
• 128031-08-3 1,3-dioxo-1-(7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4'-methoxyphenyl)-propane 
• 128031-09-4 1,3-dioxo-1-(7-hydroxy-5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(3',4'-dimethoxyphenyl)-propane 
• 5307-59-5 robustic acid 
• 22044-61-7 robustin 
• 61828-61-3 2,2-dimethyl-5-methoxy-8-(4'-methoxyphenyl)-2H,6H<1,2-b:5,4-b'>dipyran-6-one 
• 128031-11-8 2,2-dimethyl-5-methoxy-8-(3',4'-dimethoxyphenyl)-2H,6H-<1,2-b:5,4-b'>dipyran-6-one 

Relevant academic research and scientific papers

1-PHENYLETHANONE FROM ACRONYCHIA PEDUNCULATA ROOT BARK

A new arylketone, 1-phenylethanone, was isolated together with acronylin, acrovestone, bergapten, β-amyrin and three furoquinoline alkaloids from the root bark of Acronychia pedunculata. - Keywords: Acronychia pedunculata; Rutaceae; arylketone; 1-phenylethanone; furoquinoline alkaloids; acronylin; acrovestone; bergapten.

Aryllead-mediated synthesis of linear 3-arylpyranocoumarins: synthesis of robustin and robustic acid

The two naturally occurring linear 3-arylpyranocoumarins, robustin 1 and robustic acid 2, have been synthesised in nine steps from methyl 2,4,6-trihydroxyphenyl ketone, in 19percent overall yield for robustin and 18percent for robustic acid.Their synthese

AN ELEGANT SYNTHESIS OF SOME NATURALLY OCCURRING LINEAR ACETYLCHROMENES: EUPATORIOCHROMENE, METHYLEUPATORIOCHROMENE (ENCECALIN); EVODIONOL AND METHYLEVODIONOL

An elegant synthesis of linear acetylchromenes, viz eupatoriochromene, methyleupatoriochromene (encecalin), evodionol and methylevodionol, has been achieved by blocking the reactive position C-3 of the appropriate ketones with an iodo group, prenylation with 3-chloro-3-methylbut-1-yne and subsequent cyclisation.Regiospecific introduction of C-prenyl group in the less reactive position C-5 has been achieved by the reaction of the appropriate 3-iodo ketones with 2-methylbut-3-en-2-ol.The 5-prenyl ketones are also essential intermediates for the synthesis of linear acetylchromenes.

NUCLEAR ISOPRENYLATION OF POLYHYDROXYACETHOPHENONES ACID CATALYSED CONDENSATION WITH ISOPRENE

A novel method of nuclear isoprenylation leading to the exclusive formation of 2,2-dimethylchromans has been achieved by the direct condensation of polyhydroxyacetophenones with isoprene in presence of phosphoric acid.Acetylchromans, thus obtained, are dehydrogenated with DDQ to given corresponding 2,2-dimethylchromenes.Using this method, synthesis of number of naturally occuring chromenes, viz. ripariochromene A (6), eupatoriochromene (10), encecalin (11), isoevodionol (16), evodionol (17) and methylevodionol (18) has been affected.