27364-64-3Relevant academic research and scientific papers
Total Synthesis and in Vitro Anti-Tumor-Promoting Activities of Racemic Acetophenone Monomers from Acronychia trifoliolata
Morita, Chihiro,Kobayashi, Yukiko,Saito, Yohei,Miyake, Katsunori,Tokuda, Harukuni,Suzuki, Nobutaka,Ichiishi, Eiichiro,Lee, Kuo-Hsiung,Nakagawa-Goto, Kyoko
, p. 2890 - 2897 (2016/12/07)
Six acetophenone derivatives, acronyculatins I (1), J (2), K (3), L (4), N (5), and O (6), were recently isolated from Acronychia trifoliolata, and the structure of the known acronyculatin B (7) was revised. Because of the limited quantities of isolated p
AN ELEGANT SYNTHESIS OF SOME NATURALLY OCCURRING LINEAR ACETYLCHROMENES: EUPATORIOCHROMENE, METHYLEUPATORIOCHROMENE (ENCECALIN); EVODIONOL AND METHYLEVODIONOL
Ahluwalia, V. K.,Prakash, Chandra,Gupta, Ranjna
, p. 609 - 611 (2007/10/02)
An elegant synthesis of linear acetylchromenes, viz eupatoriochromene, methyleupatoriochromene (encecalin), evodionol and methylevodionol, has been achieved by blocking the reactive position C-3 of the appropriate ketones with an iodo group, prenylation with 3-chloro-3-methylbut-1-yne and subsequent cyclisation.Regiospecific introduction of C-prenyl group in the less reactive position C-5 has been achieved by the reaction of the appropriate 3-iodo ketones with 2-methylbut-3-en-2-ol.The 5-prenyl ketones are also essential intermediates for the synthesis of linear acetylchromenes.
