529-78-2 Usage
Uses
Since the provided materials do not specify any particular uses for 1,5-Methano-8H-pyrido(1,2-a)(1,4)diazocin-8-one, 3-(3-butenyl)-1,2,3,4,5,6-hexahydro-, (1R)-, it is not possible to list its applications based on the given information. However, if there were any known uses, they would be listed as follows:
Used in [Application Industry]:
1,5-Methano-8H-pyrido(1,2-a)(1,4)diazocin-8-one, 3-(3-butenyl)-1,2,3,4,5,6-hexahydro-, (1R)is used as [application type] for [application reason].
References
Manske, Marion., Can. J. Res., 20B, 265 (1942)
Manske, Marion., ibid, 21B, 144 (1943)
Cockburn, Marion., Can. J. Chem., 30,92 (1952)
van Tamelen, Baran.,J. Amer. Chem. Soc., 71,4944 (1955)
Check Digit Verification of cas no
The CAS Registry Mumber 529-78-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 529-78:
(5*5)+(4*2)+(3*9)+(2*7)+(1*8)=82
82 % 10 = 2
So 529-78-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H20N2O/c1-2-3-7-16-9-12-8-13(11-16)14-5-4-6-15(18)17(14)10-12/h2,4-6,12-13H,1,3,7-11H2/t12-,13+/m0/s1
529-78-2Relevant academic research and scientific papers
The Enantioselective Total Synthesis of Bisquinolizidine Alkaloids: A Modular “Inside-Out” Approach
Scharnagel, Dagmar,Goller, Jessica,Deibl, Nicklas,Milius, Wolfgang,Breuning, Matthias
supporting information, p. 2432 - 2435 (2018/02/16)
Bisquinolizidine alkaloids are characterized by a chiral bispidine core (3,7-diazabicyclo[3.3.1]nonane) to which combinations of an α,N-fused 2-pyridone, an endo- or exo-α,N-annulated piperidin(on)e, and an exo-allyl substituent are attached. We developed a modular “inside-out” approach that permits access to most members of this class. Its applicability was proven in the asymmetric synthesis of 21 natural bisquinolizidine alkaloids, among them more than ten first enantioselective total syntheses. Key steps are the first successful preparation of both enantiomers of C2-symmetric 2,6-dioxobispidine by desymmetrization of a 2,4,6,8-tetraoxo precursor, the construction of the α,N-fused 2-pyridone by using an enamine-bromoacrylic acid strategy, and the installation of endo- or, optionally, exo-annulated piperidin(on)es.
