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485-35-8

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Product FOB Price Min.Order Supply Ability Supplier
Top quality Cytisine
Cas No: 485-35-8
USD $ 2.0-2.0 / Gram 100 Gram 100 Metric Ton/Month Hebei yanxi chemical co.,LTD. Contact Supplier
Cytisine powder
Cas No: 485-35-8
USD $ 35.0-150.0 / Kilogram 1 Kilogram 150 Kilogram/Month Greenutra Resource Inc Contact Supplier
Cytisine
Cas No: 485-35-8
No Data 1 Gram 5000 Metric Ton/Day Kono Chem Co.,Ltd Contact Supplier
High quality Cytisine Cas 485-35-8 with best price
Cas No: 485-35-8
No Data 100 Gram 50 Kilogram/Month Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
High quality Cytisine supplier in China
Cas No: 485-35-8
No Data No Data No Data Simagchem Corporation Contact Supplier
(1R,5S)-3,4,5,6-Tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one
Cas No: 485-35-8
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
(-)-Cytisine
Cas No: 485-35-8
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Factory ?Cytisine? seller/manufacturer in stock
Cas No: 485-35-8
No Data 10 Gram 500 Kilogram/Month SHANXI JINJIN CHEMICAL INDUSTRIAL CO.,LTD Contact Supplier
Cytisine Manufacturer/High quality/Best price/In stock
Cas No: 485-35-8
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Cytisine CAS: 485-35-8
Cas No: 485-35-8
USD $ 1.0-2.0 / Metric Ton 5 Metric Ton 1000 Metric Ton/Year Henan Sinotech Import&Export Corporation Contact Supplier

485-35-8 Usage

Uses

antiinflammatory, respiratory stimulant

References

https://en.wikipedia.org/wiki/Cytisine
https://www.drugbank.ca/drugs/DB09028

Chemical Properties

Off-White to Tan Crystalline Solid

Definition

ChEBI: An organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as n aid to giving up smoking.

Purification Methods

Crystallise cytisine from acetone and sublime it in a vacuum. Its solubilities are: 77% (H2O), 7.7% (Me2CO), 28.6% (EtOH), 3.3% (*C6H6), 50% (CHCl3) but it is insoluble in pet ether. The tartrate has m 206-207o [] D +45.9o, the N-tosylate has m 206-207o, and the N-acetate has m 208o. [Bohlmann et al. Angew Chem 67 708 1955, van Tamelen & Baran J Am Chem Soc 77 4944 1955, Isolation: Ing J Chem Soc 2200 1931, Govindachari et al. J Chem Soc 3839 1957, Abs config: Okuda et al. Chem Ind (London) 1751 1961, Beilstein 24 H 134, 24 I 244, 24 II 70, 24 III/IV 321.] TOXIC.

Uses

Toxic priniciple in seed of Laburnum anagyroides and other Leguminosae. A neuronal nicotinic acetylcholine agonist

Description

Cytisine (also known as baptitoxine and sophorine) is a kind of naturally occurring alkaloid that can be found in several plant genera including Laburnum and Cytisus in the family Fabaceae. It has been shown that it is effective in the smoking cessation treatment. It is a low efficacy partial agonist of alpha4-beta2 nicotinic acetylcholine receptors, which is the central target of the nicotine that facilitates addiction. Cytisine is capable of reducing the effect of nicotine on dopamine release on the mesolimbic system as well as attenuating the nicotine withdrawal symptoms. Cytisine is also a useful reagent for organic chemistry such as being used for the manufacture of sparteine surrogate.

Biological Activity

A potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β 2-containing nicotinic receptors.
InChI:InChI=1/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/p+1/t8-,9+/m0/s1

485-35-8 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
TCI America (C2609)  (-)-Cytisine  >98.0%(GC)(T) 485-35-8 1g 3,990.00CNY Detail
TCI America (C2609)  (-)-Cytisine  >98.0%(GC)(T) 485-35-8 100mg 790.00CNY Detail

485-35-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name cytisine

1.2 Other means of identification

Product number -
Other names (-)-Cytisine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:485-35-8 SDS

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