5292-56-8

Upstream product

• 670-80-4 4-cyclohexen-1-ylmorpholine 
• 98-88-4 benzoyl chloride 
• 108-94-1 cyclohexanone 

Downstream Products

• 1427057-76-8 N-benzyl-3-thioxo-1-phenyl-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide 
• 1427057-82-6 N,1-diphenyl-3-(2-cyanoethylsulfanyl)-5,6,7,8-tetrahydroisoquinoline-4-carboxamide 
• 1427057-83-7 3-methylsulfanyl-N,1-diphenyl-5,6,7,8-tetrahydroisoquinoline-4-carboxamide 
• 1427057-84-8 3-benzylsulfanyl-N,1-diphenyl-5,6,7,8-tetrahydroisoquinoline-4-carboxamide 
• 1427057-68-8 3-oxo-1-phenyl-2-(furan-2-ylmethyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carbonitrile 
• 725710-07-6 11-phenyl-7,8,9,10-tetrahydrobenzo[4,5]imidazo[1,2-b]isoquinoline-6-carbonitrile 
• 1427057-87-1 [2-(3-hydroxyphenylamino)cyclohex-1-enyl]-(phenyl)methanone 
• 1427057-78-0 N-(2-methylphenyl)-3-thioxo-1-phenyl-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide 
• 1427057-79-1 3-thioxo-1-phenyl-N-(furan-2-ylmethyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide 
• 1427057-77-9 3-thioxo-N,1-diphenyl-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide 
• 53661-29-3 3-oxo-1-phenyl-2,3,5,6,7,8-hexahydroiso quinoline-4-carbonitrile 
• 1441050-22-1 2-[4-cyano-1-phenyl-5,6,7,8-tetrahydroisoquinolin-3(2H)-ylidene]malononitrile 
• 1441053-41-3 2-allyl-2-(4-cyano-1-phenyl-5,6,7,8-tetrahydroisoquinolin-3-yl)malononitrile 
• 1441052-06-7 ethyl 3-thioxo-1-phenyl-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxylate 

Relevant academic research and scientific papers

One-Pot Synthesis of 3-Oxocycloalka[c]pyridines

Abstract: A new efficient one-pot procedure has been developed for the synthesis of 1-substituted partially hydrogenated 3-oxocycloalka[c]pyridine-4-carbonitriles by reaction of cyclopentanone or cyclohexanone with morpholine, acyl chloride, and cyanoacetamide. The proposed procedure is advantageous due to shorter reaction time and smaller amounts of the solvents and reactants.

Synthesis and characterization of new long-wavelength-absorbing oxonol dyes from the 2,2-difluoro-1,3,2-dioxaborine type

By starting from methyl- and methylene-substituted 2,2-difluoro-1,3,2-dioxaborines 5, 20, and 21 and different types of reactive formyl derivatives (14-17) a series of anionic, cationic, and betainic methine dyes has been prepared. These dioxaborine dyes

FUNCTIONALIZED CHLOROENAMINES IN AMINOCYCLOPROPANE SYNTHESIS - V. SYNTHESIS AND REACTIONS OF AMINOCYCLOPROPYLKETONES

Conjugated acylated chloroenamines 5A,C were available by chlorination of mixtures of acylated enamines 8A,C/9A,C by NCS at 0 deg C.Nonconjugated chloroenamines 10Aa and 10Ba could be obtained by NCS-chlorination of the conjugated acylenamines 9A,B at low temperature.Reaction of 5Aa-5Ac, 5Ae, 5Af with cyanide produced morpholinocyclopropylketones 11A.In two cases aminofurans 12Ad and 12Ca resulted as products of this reaction.More generally amino-aryl-furans 12 were formed by thermolysis of the aryl-cyclopropylketones 11.Amino-alkyl-furans as 12Ae and 12Af only could be trapped by a Diels-Alder reaction leading to 16Ae and 16Af.Epoxyenamines 29A,B unexpectedly were produced from the interaction of cyanide with the chloroenamines 10Aa and 10Ba.