5293-77-6

Basic information

• Product Name: Benzene, 1,1'-(1,2-ethynediyl)bis[2-chloro-
• CAS NO: 5293-77-6
• Molecular Formula: C14H8Cl2
• Molecular Weight: 247.124
• Mol File: 5293-77-6.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(1,2-ethynediyl)bis[2-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(1,2-ethynediyl)bis[2-chloro-(5293-77-6)
• EPA Substance Registry System: Benzene, 1,1'-(1,2-ethynediyl)bis[2-chloro-(5293-77-6)

Safety Data

• Hazardous Substances Data: 5293-77-6(Hazardous Substances Data)

Upstream product

• 694-80-4 2-bromo-1-chlorobenzene 
• 142-45-0 Acetylenedicarboxylic acid 
• 615-41-8 2-iodochlorobenzene 
• 873-31-4 2-chlorophenylacetylene 
• 1066-54-2 trimethylsilylacetylene 
• 3900-89-8 2-Chlorobenzeneboronic acid 
• 1216963-74-4 lithium acetylide-ethylenediamine complex 
• 536-74-3 phenylacetylene 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 168481-89-8 3,4-bis(2-chlorophenyl)-1,2,5-oxadiazole 2-oxide 
• 563-79-1 2,3-Dimethyl-2-butene 
• 856162-07-7 (Z)-1,2-dichloro-1,2-bis(2-chlorophenyl)ethylene 

Downstream Products

• 1446486-56-1 2,3-bis(2-chlorophenyl)benzo[b]furan 
• 1631061-02-3 C₁₄H₁₈B₁₀Cl₂ 
• 1632078-29-5 1,2-bis(2-chlorophenyl)acenaphthylene 
• 1632078-35-3 7,8-bis(2-chlorophenyl)-3,4-dihydrocyclopenta[f,g]acenaphthylene 
• 21854-95-5 2,2'-dichlorobenzil 
• 57027-67-5 2-hydroxyethyl 2-chlorobenzoate 

Relevant articles and documents

Stereodivergent Synthesis of Alkenylpyridines via Pd/Cu Catalyzed C-H Alkenylation of Pyridinium Salts with Alkynes

The first Pd/Cu catalyzed selective C2-alkenylation of pyridines with internal alkynes has been developed via the pyridinium salt activation strategy. Importantly, the configuration of the product alkenylpyridines could be tuned by the choice of the proper N-alkyl group of the pyridinium salts, thus allowing for both the Z- and E-alkenylpyridines synthesized with good regio- and stereoselectivity. A plausible mechanism was proposed based on the Hammett study and KIE experiment.

Rhodium(iii)-catalyzed unreactive C(sp3)-H alkenylation of N-alkyl-1H-pyrazoles with alkynes

The first example of pyrazole-directed rhodium(iii)-catalyzed unreactive C(sp3)-H alkenylation with alkynes has been described, which showed a relatively broad substrate scope with good functional group compatibility. Moreover, we demonstrated that the transitive coordinating center pyrazole could be easily removed under mild conditions.

Dichotomy of Manganese Catalysis via Organometallic or Radical Mechanism: Stereodivergent Hydrosilylation of Alkynes

Herein, we disclose the first manganese-catalyzed hydrosilylation of alkynes featuring diverse selectivities. The highly selective formation of E-products was achieved by using mononuclear MnBr(CO)5 with the arsenic ligand, AsPh3. Whereas using the dinuclear catalyst Mn2(CO)10 and LPO (dilauroyl peroxide) enabled the reversed generation of Z-products in good to excellent stereo- and regioselectivity. Such a way of controlling the reaction stereoselectivity is unprecedented. Mechanistic experiments revealed the dichotomy of manganese catalysis via organometallic and radical pathways operating in the E- and Z-selective routes, respectively.