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Hydroxymethyl Triphenylphosphonium Chloride is a chemical compound widely used in organic synthesis, particularly as a reagent in the Wittig Reaction for synthesizing alkenes from aldehydes or ketones. It features a phosphorus atom with a positive charge, making it a versatile intermediate in various chemical reactions. HYDROXYMETHYL TRIPHENYLPHOSPHONIUM CHLORIDE is typically found in its solid state, appearing as white-to-off-white crystals. Its hydroxy or OH group also contributes to its high reactivity. Due to its potential hazards, it should be handled with care to avoid harm if swallowed, inhaled, or if it comes in contact with the skin.

5293-83-4

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5293-83-4 Usage

Uses

Used in Organic Synthesis:
Hydroxymethyl Triphenylphosphonium Chloride is used as a reagent for the Wittig Reaction, a method for synthesizing alkenes from aldehydes or ketones. Its phosphorus atom with a positive charge allows it to act as a versatile intermediate in various chemical reactions.
Used in Pharmaceutical Industry:
Hydroxymethyl Triphenylphosphonium Chloride is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its reactivity and ability to form intermediates make it a valuable component in the development of new drugs.
Used in Chemical Research:
Hydroxymethyl Triphenylphosphonium Chloride is used as a research tool in the field of chemistry, particularly in studying the properties and reactions of phosphorus-containing compounds. Its unique structure and reactivity provide insights into the behavior of similar compounds in various chemical processes.

Check Digit Verification of cas no

The CAS Registry Mumber 5293-83-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,9 and 3 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5293-83:
(6*5)+(5*2)+(4*9)+(3*3)+(2*8)+(1*3)=104
104 % 10 = 4
So 5293-83-4 is a valid CAS Registry Number.
InChI:InChI=1/C19H18OP/c20-16-21(17-10-4-1-5-11-17,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16H2/q+1

5293-83-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (Hydroxymethyl)triphenylphosphonium chloride

1.2 Other means of identification

Product number -
Other names hydroxymethyl(triphenyl)phosphanium,chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5293-83-4 SDS

5293-83-4Relevant academic research and scientific papers

The synthesis of benzylphosphine oxidesvia vicarious nucleophilic substitution and alkenes via VNS-Horner-Wittig reactions

Lawrence, Nicholas J.,Liddle, John,Jackson, David

, p. 2260 - 2267 (2007/10/03)

A range of substituted nitrobenzenes react with the anion of (chloromethyl)diphenylphosphinoyl oxide to give the substituted nitrobenzyldiphenylphosphine oxide by vicarious nucleophilic substitution. The novel stereoselective synthesis of E-stilbenes via a one-pot vicarious nucleophilic substitution-Horner-Wittig reaction is described.

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