52939-33-0

Basic information

• Product Name: N-ME-4-METHOXY-PHE-OH
• Synonyms: N-ME-TYR(ME)-OH;N-ME-TYR(ME)-OH HCL;N-ME-TYROSINE(ME)-OH;N-METHYL-4-METHOXY-L-PHENYLALANINE HYDROCHLORIDE;N-ME-P-METHOXY-PHE-OH HYDROCHLORIDE;N-ME-4-METHOXY-PHE-OH;N-ALPHA-METHYL-O-METHYL-L-TYROSINE;N-ALPHA-METHYL-4-METHOXY-L-PHENYLALANINE
• CAS NO: 52939-33-0
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.24
• Product Categories: amino acids
• Mol File: 52939-33-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 350.9±32.0 °C(Predicted)
• Appearance: /
• Density: 1.142±0.06 g/cm3(Predicted)
• Storage Temp.: Store at RT.
• PKA: 2.26±0.16(Predicted)
• CAS DataBase Reference: N-ME-4-METHOXY-PHE-OH(CAS DataBase Reference)
• NIST Chemistry Reference: N-ME-4-METHOXY-PHE-OH(52939-33-0)
• EPA Substance Registry System: N-ME-4-METHOXY-PHE-OH(52939-33-0)

Safety Data

• Hazardous Substances Data: 52939-33-0(Hazardous Substances Data)

Usage

General Description

N-ME-4-METHOXY-PHE-OH is a chemical compound with the molecular formula C9H13NO3 and a molecular weight of 179.20 g/mol. It is also known as N-methyl-4-methoxyphenethylamine and is classified as a phenethylamine derivative. N-ME-4-METHOXY-PHE-OH has a methoxy group and a methyl group attached to the phenyl ring. It is commonly used in research and pharmaceutical development as a precursor or intermediate in the synthesis of various pharmaceutical drugs and active ingredients. Its properties and potential uses are still being explored in the scientific community.

Upstream product

• 112176-77-9 5-(4-methoxy-benzyl)-1,3-dimethyl-imidazolidine-2,4-dione 
• 21405-62-9 2-(4-methoxybenzyl)malonic acid 
• 21405-61-8 2-(4-methoxybenzylidene)malonic acid 
• 73584-84-6 (S)-2-(tert-butoxycarbonyl(methyl)amino)-3-(4-methoxyphenyl)propanoic acid 
• 122621-60-7 RA-VII 
• 861545-92-8 bromo-(4-methoxy-benzyl)-malonic acid 

Downstream Products

• 19897-63-3 N-methyltyrosine 
• 1006727-52-1 C₁₁H₁₄BrNO₃ 
• 99557-34-3 3-hydroxy-4-(4'-methoxyphenyl)-2(1H)-quinolinone 
• 1357361-52-4 (-)-(S)-3-(3,5-dibromo-4-methoxyphenyl)-2-(N-methyl-2-methylprop-2-yloxycarbamoyl)propanoic acid 
• 1357361-44-4 (+)-(S)-3-(3,5-dibromo-4-methoxyphenyl)-2-methylaminopropanoic acid hydrochloride 
• 1357361-40-0 (+)-(S)-methyl 3-(3,5-dibromo-4-methoxyphenyl)-2-methylaminopropanoate 

Relevant articles and documents

Kakeromamide A, a new cyclic pentapeptide inducing astrocyte differentiation isolated from the marine cyanobacterium Moorea bouillonii

Kakeromamide A (1), a new cyclic pentapeptide encompassing a thiazole ring moiety and a β-amino acid, was isolated from the marine cyanobacterium Moorea bouillonii. Its structure was elucidated by the spectral analysis and the modified Marfey's method. Compound 1 induced differentiation of neural stem cells into astrocytes at the concentration of 10 μM.

Pompanopeptins A and B, new cyclic peptides from the marine cyanobacterium Lyngbya confervoides

A new 3-amino-6-hydroxy-2-piperidone (Ahp) containing peptolide, pompanopeptin A (1), and a novel N-methyl-2-amino-6-(4′-hydroxyphenyl)hexanoic acid (N-Me-Ahpha) containing cyclic pentapeptide connected with a sixth amino acid residue via a rare ureido linkage, pompanopeptin B (2), were isolated from the marine cyanobacterium Lyngbya confervoides collected from the southeastern coast of Florida. Their planar structures were determined by a combination of NMR spectroscopic analysis and mass spectrometry. The absolute configurations were established using advanced Marfey's method and chiral HPLC analysis of the chemical degradation products. Compound 1 selectively inhibited trypsin over elastase and chymotrypsin, with an IC50 value of 2.4 μM; selectivity is conferred by an arginine residue in the cyclic core.

Studies on the antitumor cyclic hexapeptides obtained from Rubiae radix

Antitumor cyclic hexapeptides named RA-VII, V, IV and III were isolated from the MeOH extracts of Rubia cordifolia and R. akane.