52964-30-4

Upstream product

• 526-75-0 2,3-Dimethylphenol 
• 50638-48-7 1-bromo-4-methoxy-2,3-dimethylbenzene 
• 2944-49-2 2,3-dimethylanisole 

Downstream Products

• 130662-50-9 (3-Bromo-2-hydroxymethyl-6-methoxy-phenyl)-methanol 
• 853076-98-9 2-benzyl-4-bromo-7-methoxy-2,3-dihydro-1H-isoindole 
• 256329-07-4 (S)-4-Bromo-7-methoxy-2-[(S)-3-phenyl-2-(3-phenyl-thioureido)-propionylamino]-indan-2-carboxylic acid ethyl ester 
• 256329-03-0 (S,S)-N-[4-bromo-2-(carboethoxy)-7-methoxyindan-2-yl]-2-[(N-carbo-2,2-dimethylethoxy)amino]-3-phenylpropanamide 
• 256329-02-9 (R,S)-N-[4-bromo-2-(carboethoxy)-7-methoxyindan-2-yl]-2-[(N-carbo-2,2-dimethylethoxy)amino]-3-phenylpropanamide 
• 256329-06-3 (S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-bromo-7-methoxy-indan-2-carboxylic acid ethyl ester 
• 256329-01-8 4-Bromo-7-methoxy-2-{[1-phenyl-meth-(E)-ylidene]-amino}-indan-2-carboxylic acid ethyl ester 
• 130662-49-6 Acetic acid 2-acetoxymethyl-3-bromo-6-methoxy-benzyl ester 

Relevant academic research and scientific papers

Discovery of an orally efficacious inhibitor of anaplastic lymphoma kinase

Anaplastic lymphoma kinase (ALK) is a promising therapeutic target for the treatment of cancer, supported by considerable favorable preclinical and clinical activities over the past several years and culminating in the recent FDA approval of the ALK inhib

THE SELECTIVE BENZYLIC BROMINATION OF o-XYLENES. A USEFUL SYNTHESIS OF PHTHALIDES

The free radical bromination of aryl methyl groups can be controlled by the strategic positioning of a remote stereo-electronic blocking group on the aryl ring.This tactic leads to the efficient synthesis of selectively benzylically brominated molecules which are useful synthetic intermediates.This methodology has been applied to the synthesis of some phthalides.