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53-05-4

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53-05-4 Usage

Chemical Properties

White to Off-White Solid

Uses

Different sources of media describe the Uses of 53-05-4 differently. You can refer to the following data:
1. Cortisone (C696500) derivative.
2. A normal mammalian metabolite of Cortisone (C696500).

Check Digit Verification of cas no

The CAS Registry Mumber 53-05-4 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 53-05:
(4*5)+(3*3)+(2*0)+(1*5)=34
34 % 10 = 4
So 53-05-4 is a valid CAS Registry Number.

53-05-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Tetrahydro Cortisone

1.2 Other means of identification

Product number -
Other names Pregnane-11,20-dione, 3,17,21-trihydroxy-, (3α,5β)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53-05-4 SDS

53-05-4Relevant articles and documents

C-3 GLUCOSIDURONATES OF METABOLITES OF ADRENAL STEROIDS

Mattox, Vernon R.,Goodrich, June E.,Nelson, Albert N.

, p. 23 - 34 (2007/10/02)

On treatment with methyl 2,3,4-tri-O-acetyl-1-bromo-1-deoxy-α-D-glucuronate and silver carbonate, tetrahydrocortisone 21-acetate gave the corresponding 3-glucosiduronate triacetyl methyl ester.This product was converted into the 20-semicarbazone which, by treatment with alkali to hydrolyze the ester functions and acid to hydrolyze the semicarbazone moiety, gave tetrahydrocortisone 3-glucosiduronic acid.The acid was converted into the crystalline barium salt and into the methyl ester.An analogous series of reactions was carried out on tetrahydrocortexolone 21-acetate.Treatment of the 20-semicarbazone of tetrahydrocortisone 3-glucosiduronic acid with potassium borohydride reduced the 11-oxo function to an 11β hydroxyl group; acid-catalyzed removal of the semicarbazone group produced tetrahydrocortisol 3-glucosiduronic acid which also was obtained as the barium salt and the methyl ester.

Transformation of steroids by certain strains of Catenabacterium

PREVOT,JANOT,NGUYEN-DANG-TAM

, p. 3785 - 3787 (2007/10/10)

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