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Methantheline Bromide (200 MG), also known as diethyl(2-hydroxyethyl)methylammonium bromidexanthene-9-carboxylate (Banthine Bromide), is a white, slightly hygroscopic, crystalline salt that is soluble in water, producing solutions with a pH of about 5. It is a strong muscarinic receptor blocking drug used to treat various conditions related to parasympathotonia.

53-46-3

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53-46-3 Usage

Uses

Used in Pharmaceutical Industry:
Methantheline Bromide (200 MG) is used as a muscarinic receptor antagonist for the treatment of overactive bladder syndrome, hypersalivation, and hyperhidrosis. It helps in managing the symptoms by blocking the muscarinic receptors, which are responsible for these conditions.
Used in Gastrointestinal Applications:
Methantheline Bromide (200 MG) is used as an antispasmodic agent for conditions such as gastritis, intestinal hypermotility, and cholinergic spasm. It helps in reducing the muscle contractions in the gastrointestinal tract, providing relief from pain and discomfort.
Used in Urological Applications:
Methantheline Bromide (200 MG) is used as a treatment for bladder irritability, which is a common symptom of overactive bladder syndrome. It helps in reducing the frequency and urgency of urination, improving the quality of life for patients suffering from this condition.
Used in Respiratory Applications:
Methantheline Bromide (200 MG) is used to manage hypersalivation, a condition where excessive saliva is produced, often as a side effect of certain medications or medical conditions. By blocking the muscarinic receptors, it helps in reducing the production of saliva, providing relief to the patients.
Used in Dermatological Applications:
Methantheline Bromide (200 MG) is used as a treatment for hyperhidrosis, a condition characterized by excessive sweating. By blocking the muscarinic receptors, it helps in reducing the amount of sweat produced, providing relief to patients with this condition.
Used in Pancreatic Applications:
Methantheline Bromide (200 MG) is used in the treatment of pancreatitis, an inflammatory condition of the pancreas. It helps in reducing the symptoms and complications associated with this condition by blocking the muscarinic receptors, which play a role in the regulation of pancreatic secretions.
Used in Gastrointestinal Ulcer Treatment:
Methantheline Bromide (200 MG) is used as a treatment for peptic ulcers, which are sores that develop in the lining of the stomach, esophagus, or small intestine. It helps in reducing the symptoms and promoting healing by blocking the muscarinic receptors, which are involved in the regulation of gastric acid secretion.

Clinical Use

Methantheline bromide, introduced in 1950, is a potent anticholinergicagent and acts at the nicotinic cholinergic receptors of thesympathetic and parasympathetic systems, as well as at themyoneural junction of the postganglionic cholinergic fibers.Like other quaternary ammonium drugs, methantheline bromideis absorbed incompletely from the GI tract.

Check Digit Verification of cas no

The CAS Registry Mumber 53-46-3 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 5 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 53-46:
(4*5)+(3*3)+(2*4)+(1*6)=43
43 % 10 = 3
So 53-46-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H26NO3.BrH/c1-4-22(3,5-2)14-15-24-21(23)20-16-10-6-8-12-18(16)25-19-13-9-7-11-17(19)20;/h6-13,20H,4-5,14-15H2,1-3H3;1H/q+1;/p-1

53-46-3 Well-known Company Product Price

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  • (1401001)  Methantheline bromide  United States Pharmacopeia (USP) Reference Standard

  • 53-46-3

  • 1401001-200MG

  • 4,588.74CNY

  • Detail

53-46-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name METHANTHELINE BROMIDE (200 MG)

1.2 Other means of identification

Product number -
Other names mtb51

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53-46-3 SDS

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