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1H-Indole-2-sulfonyl chloride, 1-[(2-fluorophenyl)sulfonyl]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

530116-15-5

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530116-15-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 530116-15-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,0,1,1 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 530116-15:
(8*5)+(7*3)+(6*0)+(5*1)+(4*1)+(3*6)+(2*1)+(1*5)=95
95 % 10 = 5
So 530116-15-5 is a valid CAS Registry Number.

530116-15-5Relevant academic research and scientific papers

Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands

Tong, Ling,Shankar,Chen, Lei,Rizvi, Razia,Kelly, Joseph,Gilbert, Eric,Huang, Chunli,Yang, De-Yi,Kozlowski, Joseph A.,Shih,Gonsiorek,Hipkin, R. William,Malikzay, Asra,Lunn, Charles A.,Lundell, Daniel J.

scheme or table, p. 6785 - 6789 (2010/12/20)

We report further expansion of the structure activity relationship (SAR) on the triaryl bis sulfone class of compounds (I), which are potent CB2 receptor ligands with excellent selectivity over the CB1 receptor. This study was extended to B ring changes, followed by simultaneous optimization of the A-, B-, and C-rings. Compound 42 has excellent CB2 potency, selectivity and rat exposure.

CANNABINOID RECEPTOR LIGANDS

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Page/Page column 63-64, (2008/06/13)

Compounds of Formula (I) and/or pharmaceutically acceptable salts, solvates or prodrugs thereof, or pharmaceutical compositions containing such compounds exhibit anti-inflammatory and immunomodulatory activity, and can be effective asCB2 receptor ligands in treating cancer and inflammatory, immunomodulatory or respiratory diseases or conditions.

CANNABINOID RECEPTOR LIGANDS

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Page/Page column 56, (2010/02/05)

There are disclosed compounds of the formula I: or a pharmaceutically acceptable salt of the compound, which exhibit anti-inflammatory and immunomodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds.

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