53101-95-4 Usage
Urea derivative
A compound derived from urea (a molecule containing two amine groups attached to the same carbon atom) with modifications to its structure.
Phenyl group attachment
A phenyl ring (a six-membered aromatic ring with a single hydrogen atom attached to each carbon atom) is attached to the nitrogen atom of the urea.
Pyridine ring attachment
A pyridine ring (a six-membered aromatic ring with one nitrogen atom replacing one carbon atom) is attached to the nitrogen of the phenyl group.
Medicinal chemistry application
The compound is often used in medicinal chemistry due to its potential pharmacological properties.
Strong binding affinity
1-phenyl-3-pyridin-3-ylmethylurea exhibits strong binding affinity to certain receptors and enzymes in the body.
Potential use in treatment of diseases
The compound has been studied for its potential use in the treatment of various diseases, including cancer and neurological disorders.
Ongoing research
The specific biological and pharmacological effects of 1-phenyl-3-pyridin-3-ylmethylurea are still being investigated.
Promising candidate for drug development
The unique chemical structure of 1-phenyl-3-pyridin-3-ylmethylurea makes it a promising candidate for drug development and research.
Check Digit Verification of cas no
The CAS Registry Mumber 53101-95-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,1,0 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 53101-95:
(7*5)+(6*3)+(5*1)+(4*0)+(3*1)+(2*9)+(1*5)=84
84 % 10 = 4
So 53101-95-4 is a valid CAS Registry Number.
53101-95-4Relevant academic research and scientific papers
Facile synthesis of phthalidyl fused spiro thiohydantoins through silica sulfuric acid induced oxidative rearrangement of ninhydrin adducts of thioureas
Mandal, Subhro,Pramanik, Animesh
, (2019/12/24)
A one-pot three-component sequential synthetic protocol produces structurally and biologically important phthalidyl fused spiro N,N′-disubstituted thiohydantoins from readily available aromatic isothiocyanates, primary amines and ninhydrin. In this three-step synthesis while the initial two steps are catalyst-free, in the final step silica sulfuric acid (SSA) induces an oxidative rearrangement in [3.3.0]-bicyclic 1,2-diol adducts of ninhydrin and thioureas under solvent-free condition to generate the final products spiro-fused thiohydantoins. The adequate acidity of SSA in cooperation with moderate oxidizing property promotes a facile oxidative rearrangement in 1,2-diol intermediates to produce the spiro-fused thiohydantoins with diverse functionalities. Easy recyclability of SSA, good to excellent yield of the products, wider substrate scope, shorter reaction time, solvent-free two steps out of three and high atom economy make this method attractive and practicable.
Metal ‘turn-off’, anion ‘turn-on’ gelation cascade in pyridinylmethyl ureas
Offiler, Caroline A.,Jones, Christopher D.,Steed, Jonathan W.
supporting information, p. 2024 - 2027 (2017/02/15)
Pyridinylmethyl ureas form strong gels in aromatic solvents. The gels are weakened or destroyed by addition of transition metal ions but gelation is recovered by adding bromide anions giving rise to a gel-sol-gel chemically triggered cascade.
