53104-95-3

Basic information

• Product Name: 4-HYDROXY-3-(TRIFLUOROMETHOXY)BENZALDEHYDE
• Synonyms: 4-HYDROXY-3-(TRIFLUOROMETHOXY)BENZALDEHYDE;4-Hydroxy-3-(trifluoroMethoxy)benzaldehyde, 98+%;alpha,alpha,alpha-Trifluorovanillin
• CAS NO: 53104-95-3
• Molecular Formula: C₈H₅F₃O₃
• Molecular Weight: 206.12
• Product Categories: Aromatic Aldehydes & Derivatives (substituted)
• Mol File: 53104-95-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 76.7-78.2°C
• Boiling Point: 233.9°C at 760 mmHg
• Flash Point: 95.3°C
• Appearance: /
• Density: 1.473g/cm³
• Vapor Pressure: 0.0357mmHg at 25°C
• Refractive Index: 1.512
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.90±0.43(Predicted)
• Water Solubility: Insoluble in water.
• Sensitive: Air Sensitive
• CAS DataBase Reference: 4-HYDROXY-3-(TRIFLUOROMETHOXY)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXY-3-(TRIFLUOROMETHOXY)BENZALDEHYDE(53104-95-3)
• EPA Substance Registry System: 4-HYDROXY-3-(TRIFLUOROMETHOXY)BENZALDEHYDE(53104-95-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36-43
• Safety Statements: 26-36/37
• Hazardous Substances Data: 53104-95-3(Hazardous Substances Data)

Usage

Uses

4-Hydroxy-3-(trifluoromethoxy)benzaldehyde is a fluorinated compound, which is used for biochemical research.

InChI:InChI=1/C8H5F3O3/c9-8(10,11)14-7-3-5(4-12)1-2-6(7)13/h1-4,13H

Upstream product

• 32858-93-8 2-(trifluoromethoxy)phenol 
• 100-97-0 hexamethylenetetramine 

Downstream Products

• 943153-19-3 4-formyl-2-(trifluoromethoxy)phenyl trifluoromethanesulfonate 
• 1373885-71-2 C₂₄H₂₁ClF₃NO₄ 
• 1373885-75-6 C₂₆H₂₅ClF₃NO₄ 
• 1373885-76-7 C₂₇H₂₃ClF₃NO₄ 
• 1380005-85-5 4-hydroxy-3-trifluoromethoxyphenethylamine 
• 1373885-77-8 C₂₃H₁₉ClF₃NO₄ 
• 1373885-78-9 C₂₃H₂₀F₃NO₄ 
• 1373885-79-0 C₂₄H₂₂F₃NO₅ 
• 1057217-20-5 4-benzyloxy-3-trifluoromethoxy-benzaldehyde 
• 1373885-66-5 C₁₁H₇F₃O₃ 

Relevant articles and documents

ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE

Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta- associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with Abeta pathology are provided.

Synthesis and fungicidal activity of new fluorine-containing mandelic acid amide compounds

A series of novel fluorine-containing mandelic acid amide compounds were designed and synthesized by a facile method, and their structures were characterized by 1H nuclear magnetic resonance (NMR) and high-resolution mass spectrometry. The preliminary in vivo bioassays indicated that some of the title compounds showed excellent fungicidal activities in vivo against Pseudoperonospora cubensis at the dosage of 25 mg L-1, which were comparable with the control (Mandipropamid).