53106-29-9Relevant academic research and scientific papers
Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: A new class of potent and selective acetylcholinesterase inhibitors
Barreiro, Eliezer J.,Camara, Celso A.,Verli, Hugo,Brazil-Más, Leonora,Castro, Newton G.,Cintra, Wagner M.,Aracava, Yasco,Rodrigues, Carlos R.,Fraga, Carlos A. M.
, p. 1144 - 1152 (2007/10/03)
A new family of tacrine (THA) analogues (7-9, 12), containing the azaheterocyclic pyrazolo-[4,3-d]pyridine or pyrazolo[3,4-b] [1,8]naphthyridine systems as isosteres of the quinoline ring of THA, has been synthesized. The compounds were tested in rat brai
