53130-36-2Relevant academic research and scientific papers
2-Amino-4-[3′-hydroxyphenyl]-4-hydroxybutanoic acid; A potent inhibitor of rat and recombinant human kynureninase
Walsh, Harold A.,Leslie, Pauline L.,O'Shea, Karen C.,Botting, Nigel P.
, p. 361 - 363 (2002)
A novel structural analogue of kynurenine, 2-amino-4-[3′-hydroxyphenyl]-4-hydroxybutanoic acid 6, was synthesised as an inhibitor of kynureninase. The compound had a significant inhibitory effect on kynureninase from both rat and human, giving a Ki/
