531512-26-2Relevant articles and documents
Palladium-Catalyzed, N-(2-Aminophenyl)acetamide-Assisted Ortho-Arylation of Substituted Benzamides: Application to the Synthesis of Urolithins B, M6, and M7
Reddy, M. Damoder,Blanton, Alexandra N.,Watkins, E. Blake
, p. 5080 - 5095 (2017/05/24)
Pd-catalyzed, selective, monoarylation of ortho-C-H bonds of various benzamides with aryl/heteroaryl iodides has been realized using N-(2-aminophenyl)acetamide (APA) as a new bidentate directing group for the first time. The reaction was tolerant of a wid
An inverse electron-demand diels-alder-based total synthesis of urolithin M7
Pottie, Ian R.,Nandaluru, Penchal Reddy,Bodwell, Graham J.
, p. 2245 - 2247 (2011/10/31)
Urolithin M7 was synthesized from 2-hydroxy-4-methoxybenzaldehyde in 8 steps and 48% overall yield. The key step was an inverse electron demand Diels-Alder (IEDDA) reaction between diene 10 and the enamine (7) derived from dimethoxyacetaldehyde and pyrrolidine, which generated the 6H-dibenzo[b,d]pyran- 6-one skeleton. Georg Thieme Verlag Stuttgart - New York.