531523-04-3Relevant academic research and scientific papers
Unique spirocyclopiperazinium salt. Part 4: Modification of dispirocyclopiperazinium (DSPZ) salts as analgesics
Li, Ang,Wang, Xin,Yue, Cai-Qin,Ye, Jia,Li, Chang-Ling,Li, Run-Tao
, p. 5078 - 5081 (2007)
In order to improve the analgesic activity of lead compound 7a, two series of dispirocyclopiperazinium (DSPZ) salts 9a-h, 10a-e and compounds 14, 15 were synthesized and evaluated for their in vivo analgesic activity both by acetic acid induced writhing t
