53165-32-5Relevant academic research and scientific papers
Iridium-catalyzed intermolecular allylic etherification with aliphatic alkoxides: Asymmetric synthesis of dihydropyrans and dihydrofurans
Shu, Chutian,Hartwig, John F.
, p. 4794 - 4797 (2004)
Hindered chiral ethers with one or two stereocenters are now readily available by allylic etherification of primary and secondary alkoxides (see reaction). When an Ir-phosphoramidite complex is used as the catalyst, the reaction proceeds with high regio-, enantio-, and diastereoselectivity. Np = 1-naphthyl.
