5317-66-8

Usage

Uses

Used in Pharmaceutical Industry:
2,3-Dichlorophenylacetic acid ethyl ester is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its role in this industry is crucial for the production of drugs that can address a range of health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3-Dichlorophenylacetic acid ethyl ester is utilized as a precursor in the development of compounds that can enhance crop growth and protect plants from diseases and pests, thereby improving agricultural productivity.
Used in Synthetic Organic Chemistry:
2,3-Dichlorophenylacetic acid ethyl ester is employed as a building block in synthetic organic chemistry for the creation of complex organic molecules. Its structural properties make it a valuable component in the synthesis of a variety of chemical products.
Used in Research and Development:
2,3-DICHLOROPHENYLACETIC ACID ETHYL ESTER is also used in research and development settings to explore its potential applications and to understand its interactions with biological systems, which can lead to the discovery of new uses and properties.

InChI:InChI=1/C10H10Cl2O2/c1-2-14-9(13)10(11,12)8-6-4-3-5-7-8/h3-7H,2H2,1H3

Upstream product

• 101-97-3 Ethyl 2-phenylethanoate 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 10026-13-8 phosphorus pentachloride 

Downstream Products

• 4773-57-3 (+/-)-1,1-Dichlor-1-phenyl-propan-2-ol 
• 1194-34-9 α-chlorostyrene oxide 
• 10606-73-2 ethyl 2-chloro-2-phenylacetate 
• 4773-34-6 1,1-dichloro-1-phenyl-2-propanone 
• 4773-52-8 1,1-dichloro-2-methyl-1-phenyl-propan-2-ol 
• 1125-24-2 2-phenyl-2,2-dichloroethanol 
• 61031-72-9 dichlorophenyl-acetic acid 
• 7598-13-2 dichloro-phenyl-acetic acid amide 

Relevant academic research and scientific papers

Chlorinations with Carbon Tetrachloride under Conditions of Phase Transfer Catalysis

Anion of ketones, sulfones and esters were α-chlorinated by carbon tetrachloride under conditions of phase transfer catalysis (PTC).Alcohols were unreactive.The observed products show that secondary reactions took place in many cases.The chlorination of the sulfone cis-2,5-diphenyltetrahydrothiophene-1,1-dioxide (1) occurred with inversion to give trans-2,5-dichloro-2,5-diphenyltetrahydrothiophene-1,1-dioxide (2).The structures of cis-1 and trans-2 were determined by X-ray diffraction.The reaction conditions are also applicable to brominations using bromotrichloromethane.

Molecular Rearrangements. 13. Kinetics and Mechanism of Rearrangements of Some Ring-Substituted α-Chlorostyrene Oxides and trans-β-Chlorostyrene Oxides.

The synthesis of certain phenyl-substituted derivatives of the isomeric trans-β-chlorostyrene oxides (6) and α-chlorostyrene oxides (7) are reported.The kinetics of rearrangement of 6 (X = p-CH3, H, p-Br, m-Cl, p-NO2) to phenylchloroacetaldehydes (12) in CCl4 buffered by Na2HPO4 and 7 (X = p-CH3, H, p-NO2) to ω-chloroacetophenones in CCl4 were determined by following the rates of disappearance of the α-chloro epoxide and formation of the α-chloro carbonyl product.These substituent effects at 130 deg C were correlated with ?+ constants, yielding ρ values of-3.5 and -0.57 for the rearrangements of 6 and 7, respectively.In nitrobenzene solvent, the kC6H5NO2/kCCl4 for 6 was 180 and for 7 was 1740, the latter solvent effect attributed to nucleophilic solvent participation.It was concluded that these thermal rearrangements of 6 and 7 occur by disrotatory Cβ-O bond heterolysis to yield the corresponding α-keto carbonium-chloride ion pairs.