53180-92-0

Basic information

• Product Name: 5-AMINO-4-CHLOROPYRIDAZINE
• Synonyms: 5-AMINO-4-CHLOROPYRIDAZINE;5-chloropyridazin-4-aMine;5-AMaino-4-chloropyridazine;4-Amino-5-chloropyridazine
• CAS NO: 53180-92-0
• Molecular Formula: C₄H₄ClN₃
• Molecular Weight: 129.55
• Mol File: 53180-92-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 70-73 °C(Solv: benzene (71-43-2))
• Boiling Point: 326.9±22.0 °C(Predicted)
• Appearance: /
• Density: 1.437±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.50±0.10(Predicted)
• CAS DataBase Reference: 5-AMINO-4-CHLOROPYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-4-CHLOROPYRIDAZINE(53180-92-0)
• EPA Substance Registry System: 5-AMINO-4-CHLOROPYRIDAZINE(53180-92-0)

Safety Data

• Hazardous Substances Data: 53180-92-0(Hazardous Substances Data)

Usage

General Description

5-Amino-4-chloropyridazine is a chemical compound with the formula C4H3ClN4. It is a pale yellow solid that is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. 5-AMINO-4-CHLOROPYRIDAZINE is a derivative of pyridazine, which is a heterocyclic organic compound containing a six-member ring with two adjacent nitrogen atoms. 5-Amino-4-chloropyridazine is known for its potential use as an intermediate in the production of various drugs and pesticides. It is also of interest to researchers in the field of organic chemistry due to its unique structure and reactivity.

Upstream product

• 20744-39-2 4-aminopyridazine 

Downstream Products

• 1466574-75-3 5-(4-fluoro-2-methoxyphenyl)pyridazin-4-ylamine 

Relevant articles and documents

Synthesis method of 5-chloro-4-aminopyridazine

The invention relates to the technical field of chemical synthesis, and concretely discloses a synthesis method of 5-chloro-4-aminopyridazine. The synthesis method comprises the following steps: 3,6-dichloro-4-aminopyridazine used as an initial raw material undergoes hydrodechlorination to obtain a 4-aminopyridazine key intermediate at a high yield, and then the key intermediate is chlorinated with N-chlorosuccinimide (NCS) to obtain the target product 5-chloro-4-aminopyridazine. The 5-chloro-4-aminopyridazine is a key intermediate for drug synthesis, but the synthesis route of 5-chloro-4-aminopyridazine, especially the synthesis route suitable for commercial mass production, is not reported. The synthesis method of the target compound is provided for the first time, is particularly suitable for commercial mass production, and allows the 5-chloro-4-aminopyridazine to be prepared with high yield and high purity.