5319-75-5Relevant academic research and scientific papers
Antimicrobial activity of newly synthesized 2,5-disubstituted 1,3,4-thiadiaozle derivatives
Ramiz, Mahmoud M. M.,Abdel-Rahman, Adel A.-H.
, p. 4227 - 4232 (2012/02/16)
A number of new 2,5-disubstituted 1,3,4-thiadiazole and their S- or N-substituted derivatives as well as the corresponding sugar hydrazone derivatives were synthesized and tested for their antimicrobial activity against Bacillus subtilis (Gram-positive),
A new route to 1,2,4-triazoles and 1,3,4-thiadiazoles from 1-acylbithiourea
Okawara,Tateyama,Yamasaki,Furukawa
, p. 1071 - 1075 (2007/10/02)
The intramolecular cyclization of 1-acylbithiourea 1 gave 1,2,4-triazole 2 and 1,3,4-thiadiazole 3. The reaction of 1 with p-toluenesulfonyl chloride in the presence of triethylamine afforded 3. Treatment of 1 with methyl iodide in the absence of any base yielded 2-methylthio-1,3,4-thiadiazole 10 and 2-imino-1,3,4-thiadiazoline 12.
