53219-49-1

Basic information

• Product Name: 1,8(2H,5H)-Acridinedione, 3,4,6,7-tetrahydro-3,3,6,6-tetramethyl-9-phenyl-
• CAS NO: 53219-49-1
• Molecular Formula: C23H25NO2
• Molecular Weight: 347.457
• Mol File: 53219-49-1.mol

Chemical Properties

• CAS DataBase Reference: 1,8(2H,5H)-Acridinedione, 3,4,6,7-tetrahydro-3,3,6,6-tetramethyl-9-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8(2H,5H)-Acridinedione, 3,4,6,7-tetrahydro-3,3,6,6-tetramethyl-9-phenyl-(53219-49-1)
• EPA Substance Registry System: 1,8(2H,5H)-Acridinedione, 3,4,6,7-tetrahydro-3,3,6,6-tetramethyl-9-phenyl-(53219-49-1)

Safety Data

• Hazardous Substances Data: 53219-49-1(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 126-81-8 dimedone 
• 141-97-9 ethyl acetoacetate 
• 23865-30-7 1,1'-phenylmethanediyl-bis-urea 

Relevant articles and documents

Synthesis and biological evaluation of new series 1,4-dihydropyridines

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DPTA-catalyzed one-pot regioselective synthesis of polysubstituted pyridines and 1,4-dihydropyridines

With diphenylammonium triflate (DPAT) as a catalyst, the highly substituted pyridines and dihydropyridines were prepared under solvent-free conditions from aldehydes, ketones, and amines via a one-pot multi-component reaction. The advantages of this protocol include excellent yields, environmentally benign source of nitrogen, mild reaction conditions, and simple manipulation. Different source of nitrogen like urea, thiourea, inorganic ammonium salts, and organic amines were studied. In addition, a novel way was developed for the conversion of primary aliphatic amines into alcohols.

Microwave assisted combinatorial chemistry. Synthesis of substituted pyridines

A new highly efficient MICROCOS technology (Microwave-assisted Combinatorial Synthesis) for generating combinatorial libraries is described. The technology is applied to the high throughput, automated, one-step, parallel synthesis of diverse substituted pyridines using the Hantzsch synthesis. The advantages of microwave-assisted chemistry for combinatorial synthesis include a broad range of available chemistries, simple reaction setup and product recovery readily amenable to automation, extremely short reaction times, and high product yields.

UREAS IN ORGANIC SYNTHESIS. III. SYNTHESIS OF 1,4-DIHYDROPYRIDINES AND HYDROGENATED ACRIDINE-1,8-DIONES BY REACTION OF 1,3-DICARBONYL COMPOUNDS WITH ARYLIDENEBISUREAS

It was found that arylidenebisureas react with dimedone in acetic acid with the simultaneous formation of 9-aryltetramethyldecahydroacridine-1,8-diones and 9-aryltetramethyloctahydroacridine-1,8-diones in a ratio of 1:2.In the reaction of benzylidenebisurea with dimedone in formic acid 3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dione s formed in addition to the hydrogenated 9-phenyltetramethylacridine-1,8-diones.