53219-49-1Relevant articles and documents
Synthesis and biological evaluation of new series 1,4-dihydropyridines
Ghorbani-Vaghei, Ramin,Malaekehpoor, Seyedeh Mina,Hasanein, Parisa,Karamyan, Roya,Asadbegy, Mostafa
, p. 4715 - 4731 (2016/07/06)
Abstract: N,N,N′,N′-Tetrachlorobenzene-1,3-disulfonamide and poly(N,N′-dichloro-N-ethyl-benzene-1,3-disulfonamide) are new catalysts promoted by one-pot, facile and four-component synthesis of new substituted 1,4-dihydropyridine derivatives from the react
Microwave assisted combinatorial chemistry. Synthesis of substituted pyridines
Cotterill, Ian C.,Usyatinsky, Alexander Ya.,Arnold, John M.,Clark, Douglas S.,Dordick, Jonathan S.,Michels, Peter C.,Khmelnitsky, Yuri L.
, p. 1117 - 1120 (2007/10/03)
A new highly efficient MICROCOS technology (Microwave-assisted Combinatorial Synthesis) for generating combinatorial libraries is described. The technology is applied to the high throughput, automated, one-step, parallel synthesis of diverse substituted pyridines using the Hantzsch synthesis. The advantages of microwave-assisted chemistry for combinatorial synthesis include a broad range of available chemistries, simple reaction setup and product recovery readily amenable to automation, extremely short reaction times, and high product yields.