53233-87-7Relevant academic research and scientific papers
CHEMICAL PROCESS FOR PREPARING PHENYLPIPERIDINYL INDOLE DERIVATIVES
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Page/Page column 50, (2020/02/14)
The present invention relates to a method of synthesizing a compound of formula (I) also referred to as 4-((2S,4S)-(4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl))benzoic acid, or a pharmaceutically acceptable salt thereof, and/or intermediates thereof, their use as pharmaceuticals and pharmaceutical compositions and the use of intermediates for preparing a compound of formula (I), or a pharmaceutically acceptable salt thereof.
2-(1H-INDOL-4-YLMETHYL)-3H-IMIDAZO[4,5-B]PYRIDINE-6-CARBONITRILE DERIVATIVES AS COMPLEMENT FACTOR B INHIBITORS USEFUL FOR THE TREATMENT OF OPHTHALMIC DISEASES
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Page/Page column 70, (2014/09/29)
The present invention provides a compound of formula (I): wherein X is N or CH, Y is NH, O or S, methods for manufacturing these compounds, and their uses as Factor B inhibitors for the treatment of conditions and diseases associated with complement alternative pathway activation such as age-related macular degeneration, diabetic retinopathy and related ophthalmic diseases. The present invention further provides pharmaceutical compositions and combinations of pharmacologically active agents.
Complement pathway modulators and uses thereof
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Paragraph 0765, (2013/11/19)
The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
