5325-37-1

Usage

Uses

Used in Traditional Medicine:
(2Z)-3-(4-hydroxyphenyl)-2-methylprop-2-enoic acid is used as a therapeutic agent for its potential antioxidant, anti-inflammatory, and anti-cancer properties. It has been utilized in traditional medicine to address various health conditions due to its natural healing properties.
Used in Food Preservation:
(2Z)-3-(4-hydroxyphenyl)-2-methylprop-2-enoic acid is used as a food preservative to extend the shelf life of various food products. Its natural antioxidant properties help in preventing the oxidation and spoilage of food items, ensuring their freshness and quality.
Used in Cosmetic and Skincare Products:
(2Z)-3-(4-hydroxyphenyl)-2-methylprop-2-enoic acid is used as an ingredient in cosmetic and skincare products for its potential antioxidant and anti-inflammatory properties. It can help in maintaining the health and appearance of the skin, providing protection against environmental stressors and promoting a youthful complexion.
Used in Pharmaceutical Industry:
(2Z)-3-(4-hydroxyphenyl)-2-methylprop-2-enoic acid is used as a precursor in the synthesis of lignin and lignan, which are important components in the pharmaceutical industry. Its potential use in the development of new drugs and therapies makes it a valuable compound for research and development in this field.

Upstream product

• 516-05-2 methyl-propanedioic acid 
• 123-08-0 4-hydroxy-benzaldehyde 
• 327-62-8 potassium propionate 
• 123-62-6 propionic acid anhydride 
• 120743-99-9 p-[(tert-butyldimethylsilyl)oxy]benzaldehyde 
• 930106-42-6 C₁₈H₂₈O₃Si 
• 50906-06-4 C₁₂H₁₄O₃ 

Downstream Products

• 1579197-44-6 C₄₂H₇₄O₁₀Si₃ 
• 1579198-21-2 C₄₂H₆₄N₆O₁₁Si₂ 
• 1579197-48-0 C₄₀H₇₂O₉Si₃ 
• 1579197-51-5 C₃₆H₆₂O₉Si₂ 
• 1579197-53-7 C₄₀H₇₀O₉Si₃ 
• 1579197-55-9 C₄₁H₇₂O₉Si₃ 
• 1579197-57-1 C₄₁H₇₂O₉Si₃ 
• 1579197-59-3 C₁₈H₂₀O₉ 
• 1579198-19-8 C₅₄H₉₂N₆O₁₁Si₄ 
• 1579198-23-4 C₅₃H₉₂N₆O₁₀Si₄ 
• 1579198-25-6 C₆₈H₁₁₀N₆O₁₅Si₄ 
• 37305-78-5 A₂₀₁A 
• 1579198-28-9 C₁₈H₂₀O₉ 
• 1579198-30-3 C₃₀H₃₆N₆O₁₁ 

Relevant academic research and scientific papers

Synthesis, characterization and antitumor potential of cinnamoyl urea derivatives

Cinnamoyl ureas have been identified as novel compounds with their various biological activities. Some novel cinnamoyl ureas were synthesized successfully by these substitutions, at the phenyl ring, at α,β -unsaturated carbon and the substitution at the c

Synthesis of Albicidin Derivatives: Assessing the Role of N-terminal Acylation on the Antibacterial Activity

The peptide antibiotic albicidin, which is synthesized by the plant pathogenic bacterium, Xanthomonas albilineans, represents the most prominent member of a new class of antibacterial gyrase inhibitors. It shows remarkable antibacterial activities against Gram-positive and Gram-negative microorganisms. Its unique structure potentially represents a new lead structure for the development of an antibacterial drug. Here we report the synthesis of 14 albicidin derivatives with structural variations at the N-terminus, primarily investigating the effects of variation of cinnamoyl, phenylpropanoyl, and benzoyl residues. Gyrase inhibition in vitro and determination of minimal inhibitory concentrations were assessed in parallel. Activities in a nanomolar range and the importance of N-acylation were demonstrated.

Total synthesis of nucleoside antibiotic A201A

A201A, a unique nucleoside antibiotic with potent antibacterial activities, has been synthesized for the first time in a total of 47 steps in a highly modular and linear manner, highlighting the elaboration/incorporation of an unprecedented hexofuranoside unit bearing an exocyclic enol ether moiety.

Analogue chromophore study of the influence of electronic perturbation on color regulation of photoactive yellow protein

We report a unique λmax shift of the absorption maximum of a photoactive yellow protein (PYP) analogue reconstituted with a fluorinated chromophore (F-PYP). The difference in λmax between the free chromophore and the protein was sign

Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4

The criteria for the activity of 2-{4-[(7-chloro-2-quinoxalinyl)oxy] phenoxy}propionic acid (XK469) and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy} propionic acid (SH80) against transplanted tumors in mice established in previous studies, require a (7-halo-2

A new nonpeptide tachykinin NK1 receptor antagonist isolated from the plants of compositae

To find new tachykinin NK1 receptor antagonists from natural sources, we examined the tachykinin antagonist activity in the extracts of approximately 200 species of plants by the use of isolated guinea pig ileum. As a result, we discovered a no

Phenylcarboxylic acid derivatives

Phenylcarboxylic acid derivatives having the formula: STR1 wherein R1 and R2 are each H, halogen, alkyl, haloalkyl, alkanoyl, cycloalkyl, nitro, amino, --O--D--R5 (D is alkylene, R5 is H, amino, morpholino, carboxyl, phthalimido, phenyl, epoxy), substituted or unsubstituted phenoxy, substituted or unsubstituted phenylalkylamino, carboxylalkenyl, or both form alkylenedioxy; R3 is H, --E--R6 (E is alkylene, R6 is H, carboxyl, cyano, OH, phenylalkoxy, or halogen-substituted phenyl, or phenylcarbamoyl), --CO--G--R7 (G is alkylene, R7 is H, substituted or unsubstituted phenylcarbamoyl), substituted or unsubstituted benzoyl, alkenyl, carbamoyl, phenyl, or halophenyl; R4 is H or alkyl; A is alkylene, alkylene condensed with cycloalkyl ring, or alkenylene; B is alkylene or alkenylene; l is 0 or 1. Said compounds have fatty acid synthesis-inhibitory activity, cholesterol synthesis-inhibitory activity and are useful as antilipidemic agent, prophylactic and treating agent of artherosclerosis, prophylactic and treating agent of obesity, antidiabetics.

Alpha-methylcinnamic acid ester derivative and liquid crystal composition

Disclosed is an α-methylcinnamic acid ester derivative represented by the formula: STR1 wherein n is an integer of from 5 to 18, R1 represents an optically active group of the formula STR2 in which m is an integer of from 1 to 5 and *C represen