53258-90-5

Upstream product

• 69798-73-8 1-Acetoxy-3-brom-3-phenyl-2-propanon 
• 108-98-5 thiophenol 
• 53258-88-1 1-chloro-3-phenyl-3-phenylthio-2-propanone 
• 127-08-2 potassium acetate 
• 85660-55-5 1-chloro-3-deuterio-3-phenyl-3-phenylthio-2-propanone 
• 64-19-7 acetic acid 
• 69798-58-9 1-diazo-3-phenyl-3-phenylthio-2-propanone 
• 36960-03-9 2-oxo-3-phenylpropyl acetate 

Relevant academic research and scientific papers

NUCLEOPHILIC SUBSTITUTION OF α-HALO-KETONES-XXII ACETOLYSIS OF α'-PHENOXY-α-CHLORO-KETONES. A COMPARISON OF THEIR REACTIVITY WITH THAT OF THE CORRESPONDING THIOETHERS

The results obtained in the acetolysis of α-chloro-ketones 1 a-e are compared with those previously reported for the acetolysis of the corresponding α'-phenylthio-α-chloro-ketones 15a-e and discussed in terms of the enolization-solvolysis mechanisms.

NUCLEOPHILIC SUBSTITUTION OF α-HALO KETONES. XXI. STRUCTURE-REACTIVITY RELATIONSHIPS IN THE ACETOLYSIS OF 3-SUBSTITUTED 1-CHLORO-3-PHENYLTHIO-2-PROPANONES

The acetolyses of α-chloro ketones 1a-d have been re-investigated under standard conditions and compared with those of the corresponding isomeric substrates 2a-d.It has been shown that participation by the neighbouring phenylthio group, involving a 1-3 shift of the latter, does occur in part even in the case of 1d, while it is the only process in the case of 1e.A few structure-reactivity relationships in the two series of substrates are discussed.