53312-76-8

Basic information

• Product Name: 3-amino-2-chlorobenzonitrile
• Synonyms: 3-amino-2-chlorobenzonitrile
• CAS NO: 53312-76-8
• Molecular Weight: 152.583
• Mol File: 53312-76-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-amino-2-chlorobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-2-chlorobenzonitrile(53312-76-8)
• EPA Substance Registry System: 3-amino-2-chlorobenzonitrile(53312-76-8)

Safety Data

• Hazardous Substances Data: 53312-76-8(Hazardous Substances Data)

Upstream product

• 34662-24-3 3-nitro-2-chlorobenzonitrile 

Relevant articles and documents

In Situ Synthesized Silica-Supported Co@N-Doped Carbon as Highly Efficient and Reusable Catalysts for Selective Reduction of Halogenated Nitroaromatics

Silica-supported Co@N-doped carbon (Co@CN/SiO2) catalysts were first prepared by a one-step impregnation with a mixed solution of cobalt nitrate, glucose and urea, followed by in situ carbonization and reduction. The Co@CN/SiO2 catalysts were investigated for the selective reduction of nitro aromatics to the corresponding anilines using hydrazine hydrate. The Co@CN/SiO2-500 carbonized at 500 °C exhibited the highest catalytic activity and excellent stability without any decay of activity after 6 cycles for the reduction of nitrobenzene. Both metallic Co atoms and Co?N species formed in the Co@CN/SiO2 catalysts were active, but the Co?N species were dominant active sites. The high activities of the Co@CN/SiO2 catalysts were attributed to the synergistic effect between the Co and N atoms, promoting heterolytic cleavage of hydrazine to form H+/H? pairs. Representative examples demonstrated that the Co@CN/SiO2-500 could completely transform various halogen-substituted nitro aromatics to the corresponding halogenated anilines with high TOFs and selectivity of '99.5 percent.