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6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one, also known as roscovitine, is a chemical compound with potential pharmacological effects. It is a potent and selective inhibitor of cyclin-dependent kinases (CDKs), which play a crucial role in regulating the cell cycle and cell proliferation.

5334-35-0

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5334-35-0 Usage

Uses

Used in Cancer Treatment:
6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one is used as an anticancer agent for its ability to block the growth of cancer cells by disrupting the cell cycle. It has been studied for its potential use in treating various types of cancer.
Used in Neurological Disorders Treatment:
6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one is used as a modulator of certain kinases involved in neuronal function, making it a potential treatment for neurological disorders.
Used in Antiviral Therapy:
6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one is used as an antiviral agent for its potential to interfere with the replication of certain viruses, offering a therapeutic option for viral infections.

Check Digit Verification of cas no

The CAS Registry Mumber 5334-35-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,3 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5334-35:
(6*5)+(5*3)+(4*3)+(3*4)+(2*3)+(1*5)=80
80 % 10 = 0
So 5334-35-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H5ClN4O/c1-11-4-3(2-8-11)5(12)10-6(7)9-4/h2,8H,1H3

5334-35-0Relevant academic research and scientific papers

PYRAZOLOPYRIMIDONE AND PYRAZOLOPYRIDONE INHIBITORS OF TANKYRASE

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Page/Page column 85, (2014/01/08)

There are provided compounds of the formula (I) or a pharmaceutically acceptable salt thereof, wherein Q, R1 and R2 are as defined herein. The compounds of formula I are useful in the treatment of cancer.

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