5334-38-3

Basic information

• Product Name: 5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID
• Synonyms: AKOS 90438;5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID;5-Methyl-4-nitro-2H-pyrazole-3-carboxylic acid;3-Methyl-4-nitro-1H-pyrazole-5-carboxylic acid, 3-Carboxy-5-methyl-4-nitro-2H-pyrazole;5-Methyl-4-nitro-2H-pyrazole-3-carboxylic acid 95%
• CAS NO: 5334-38-3
• Molecular Formula: C₅H₅N₃O₄
• Molecular Weight: 171.11
• Mol File: 5334-38-3.mol

Chemical Properties

• Melting Point: 185 °C
• Boiling Point: 466.2°C at 760 mmHg
• Flash Point: 235.8°C
• Appearance: /
• Density: 1.683g/cm³
• Vapor Pressure: 1.71E-09mmHg at 25°C
• Refractive Index: 1.65
• Storage Temp.: 2-8°C
• PKA: 1.48±0.35(Predicted)
• CAS DataBase Reference: 5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID(5334-38-3)
• EPA Substance Registry System: 5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID(5334-38-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5334-38-3(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID is used as a synthetic intermediate for the preparation of various organic compounds, leveraging its reactivity and structural features to facilitate the synthesis of a wide range of chemical entities.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID is used as a key component in the development of new drugs, owing to its potential pharmacological properties and biological activities. Its unique structure allows it to be a candidate for the treatment of various diseases and conditions.
Used in Agrochemical Industry:
5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID is utilized as a building block in the agrochemical industry for the synthesis of pesticides and other agrochemical products, contributing to its potential reactivity and versatility in this field.
Used in Materials Science:
In materials science, 5-METHYL-4-NITRO-1H-PYRAZOLE-3-CARBOXYLIC ACID is employed in the development of new materials with specific properties, such as high thermal stability or unique electronic characteristics, due to its chemical structure and potential reactivity.

InChI:InChI=1/C5H5N3O4/c1-2-4(8(11)12)3(5(9)10)7-6-2/h1H3,(H,6,7)(H,9,10)

Upstream product

• 31618-80-1 3-methyl-5-thiophen-2yl-1-hydropyrazole 
• 696-22-0 5-methyl-2H-pyrazole-3-carboxylic acid 
• 4027-57-0 ethyl 5-methyl-2H-pyrazole-3-carboxylate 
• 3051-27-2 1-(2-thienyl)-1,3-butanedione 
• 402-61-9 5-methyl-1H-pyrazole-3-carboxylic acid 

Downstream Products

• 101535-72-2 4-amino-3-(2-benzyloxyethoxy)methyl-5-cyanopyrazole 
• 101535-71-1 4-amino-3-(2-benzyloxyethoxy)methylpyrazole-5-carboxamide 
• 101535-73-3 7-amino-3-(2-benzyloxyethoxy)methylpyrazolo<4,3-d>pyrimidine 
• 101535-76-6 4-Amino-5-(2-benzyloxy-ethoxymethyl)-2H-pyrazole-3-carboxylic acid isopropyl ester 
• 101535-77-7 3-(2-benzyloxyethoxy)methylpyrazolo<4,3-d>pyrimidin-7(6H)-one 
• 101535-70-0 3-(2-benzyloxyethoxy)methyl-4-nitropyrazole-5-carboxamide 
• 101535-69-7 isopropyl-3-(2-benzyloxyethoxy)methyl-4-nitropyrazole-5-carboxylate 
• 101535-80-2 4-(3-Benzoyl-2-methyl-isothioureido)-5-(2-benzyloxy-ethoxymethyl)-2H-pyrazole-3-carboxylic acid amide 
• 101535-79-9 4-(N'-benzoylthioureido)amino-3-(2-benzyloxyethoxymethyl)pyrazole-5-carboxamide 
• 82231-52-5 4-bromo-5-methyl-1⁽²⁾H-pyrazole-3-carboxylic acid 
• 6076-14-8 4-bromo-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 1043909-04-1 4-bromo-5-methyl-1(2)H-pyrazole-3-carboxylic acid hydrazide 
• 68375-43-9 5-methyl-4-nitro-1⁽²⁾H-pyrazole-3-carboxylic acid methylamide 
• 68375-44-0 4-amino-5-methyl-1⁽²⁾H-pyrazole-3-carboxylic acid methylamide 

Relevant articles and documents

Synthesis and anti-TMV activity of novel N-(3-alkyl-1H-pyrazol-4-yl)-3- alkyl-4-substituted-1H-pyrazole-5-carboxamides

In order to investigate the biological activity of novel bis-pyrazole compounds, a series of N-(3-alkyl-5-(N-methylcarbamyl)-1H-pyrazol-4-yl)-3-alkyl- 4-substituted-1H-pyrazole-5-carboxamides were designed and synthesized with ethyl 3-alkyl-1H-pyrazole-5-