5335-23-9

Usage

Synonyms

4-CPP

Chemical classification

Chlorinated derivative of phenylpropanolamine

Category

Sympathomimetic drug

Use

Appetite suppressant

Additional use

Intermediate in the synthesis of pharmaceuticals and other organic compounds

Physical state

Colorless liquid

Odor

Slightly sweet

Solubility

Slightly soluble in water

Toxicity

Moderately toxic

Handling precautions

Exercise caution when handling and using

Regulatory status

Regulated and controlled due to potential for misuse and abuse as a drug

Upstream product

• 1193-00-6 sodium 4-chlorophenolate 
• 127-00-4 1-Chloro-2-propanol 
• 106-48-9 4-chloro-phenol 
• 75-56-9 methyloxirane 
• 18859-35-3 4-chlorophenoxyacetone 

Downstream Products

• 17964-65-7 me3SiOCH(CH₃)CH₂Oph-4-Sime₃ 
• 56219-95-5 1-(p-chlorophenoxy)-propan-2-ol pivalate 
• 69183-26-2 Methanesulfonic acid 2-(4-chloro-phenoxy)-1-methyl-ethyl ester 
• 56219-97-7 Isobutyric acid 2-(4-chloro-phenoxy)-1-methyl-ethyl ester 
• 56219-96-6 3-Methyl-butyric acid 2-(4-chloro-phenoxy)-1-methyl-ethyl ester 
• 18057-06-2 me3Si(ph-4-(pr-2-OH)) 
• 69183-27-3 {4-[2-(4-Chloro-phenoxy)-1-methyl-ethoxy]-phenyl}-acetic acid methyl ester 

Relevant academic research and scientific papers

Selective Cross-Dehydrogenative C(sp3)-H Arylation with Arenes

Selective C(sp3)-C(sp2) bond construction is of central interest in chemical synthesis. Despite the success of classic cross-coupling reactions, the cross-dehydrogenative coupling between inert C(sp3)-H and C(sp2)-H bonds represents an attractive alternative toward new C(sp3)-C(sp2) bonds. Herein, we establish a selective inter-and intramolecular C(sp3)-H arylation of alcohols with nondirected arenes that thereby provides a general pathway to access a wide range of β-arylated alcohols, including tetrahydronaphthalen-2-ols and benzopyran-3-ols, with high to excellent chemo-and regioselectivity.

An efficient catalyst for ring opening of epoxides with phenol and thiophenol under solvent-free conditions

An efficient and rapid procedure for ring opening reaction of various epoxides with phenol and thiophenol derivatives was developed. The procedure can be obtained at room temperature under solvent-free condition in presence of (C4H12N2)2[BiCl6] Cl·H2O (1 mol %). This catalyst can be reused several times without significant loss of activity.

β-Phenoxy or substituted phenoxy ethanol compounds

Novel β-phenoxy- or substituted phenoxy-ethanol compounds or esters thereof expressed by the formula STR1 wherein R1 is a hydrogen atom or an alkyl group, R2 is a hydrogen atom or a substituent, Y is --OH group or group STR2 R3 is an alkyl group, and n is an integer of 1 to 3. These compounds have juvenile hormone activities, and are useful for hormonal pest control and increased production of silkworm cocoons.