5335-40-0

Basic information

• Product Name: 3-(METHYLSULFONYL)BENZENESULFONYLCHLORIDE
• Synonyms: 3-mesylbenzenesulfonyl chloride;3-(Chlorosulphonyl)phenyl methyl sulphone;3-(Methylsulfonyl)benzene-1-sulfonyl chloride
• CAS NO: 5335-40-0
• Molecular Formula: C₇H₇ClO₄S₂
• Molecular Weight: 254.71
• Mol File: 5335-40-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 93～96℃
• Boiling Point: 449.7°Cat760mmHg
• Flash Point: 225.8°C
• Appearance: /
• Density: 1.517g/cm³
• Vapor Pressure: 7.44E-08mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-(METHYLSULFONYL)BENZENESULFONYLCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(METHYLSULFONYL)BENZENESULFONYLCHLORIDE(5335-40-0)
• EPA Substance Registry System: 3-(METHYLSULFONYL)BENZENESULFONYLCHLORIDE(5335-40-0)

Safety Data

• Hazardous Substances Data: 5335-40-0(Hazardous Substances Data)

Usage

General Description

3-(Methylsulfonyl)benzenesulfonyl chloride is a chemical compound with the molecular formula C7H7ClO2S2. It is a sulfonating agent that is commonly used in organic synthesis and industrial processes. 3-(METHYLSULFONYL)BENZENESULFONYLCHLORIDE is a versatile molecule that can be used to introduce sulfonyl groups into various organic molecules, and it is known for its reactivity with a wide range of substrates. It is highly important in the pharmaceutical industry for the synthesis of sulfa drugs and other pharmaceutical compounds. Additionally, it has applications in the manufacturing of dyes, pigments, and other specialty chemicals. However, it is important to handle 3-(Methylsulfonyl)benzenesulfonyl chloride with care, as it is a strong irritant and can cause severe skin and eye irritation.

InChI:InChI=1/C7H7ClO4S2/c1-13(9,10)6-3-2-4-7(5-6)14(8,11)12/h2-5H,1H3

Upstream product

• 3112-85-4 methylphenylsulfonate 

Downstream Products

• 22821-87-0 3-Methansulfonyl-benzolsulfinsaeure 
• 22821-81-4 methyl phenyl sulfone-3-sulfonic acid 
• 111711-75-2 5-Ethoxy-1-(3-methanesulfonyl-benzenesulfonyl)-pyrrolidin-2-one 
• 20020-30-8 O-(3-Methylsulfonyl-benzolsulfonyl)-2-(4-nitro-phenyl)-aethanol 
• 1165803-22-4 C₁₄H₁₂N₂O₄S₂ 
• 881676-54-6 1-{[3-(methylsulfonyl)phenyl]sulfonyl}-5-phenyl-1H-pyrrole-3-carbaldehyde 
• 1138034-09-9 sodium 3-(methylsulfonyl)benzenesulfinate 
• 1046353-88-1 5'-deoxy-5'-[3-(methylsulfonyl)benzenesulfonamido]thymidine 
• 881677-13-0 1-{[3-(methylsulfonyl)phenyl]sulfonyl}-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carbaldehyde 
• 881677-02-7 5-(2-fluorophenyl)-1-{[3-(methylsulfonyl)phenyl]sulfonyl}-1H-pyrrole-3-carbaldehyde 
• 881677-17-4 5-(2-methylphenyl)-1-{[3-(methylsulfonyl)phenyl]sulfonyl}-1H-pyrrole-3-carbaldehyde 
• 881675-02-1 methyl 5-bromo-1-{[3-(methylsulfonyl)phenyl]sulfonyl}-1H-pyrrole-3-carboxylate 
• 881677-30-1 4-methyl-1-{[3-(methylsulfonyl)phenyl]sulfonyl}-5-phenyl-1H-pyrrole-3-carbaldehyde 

Relevant articles and documents

NITRIC OXIDE-RELEASING PRODRUG MOLECULE

Provided are a type of compounds that can be used for treating cardiovascular diseases and compositions containing the compounds. The compounds and the compositions can improve lipid metabolism disorders by increasing high-density lipoprotein cholesterol in blood; in addition, the compounds and the compositions can also release nitric oxide, and reduce the onset risk of cardiovascular diseases by means of relaxing blood vessels, lowering blood pressure, inhibiting platelet adhesion and aggregation and maintaining vascular tension, and thus play an important role in preventing and treating the occurrence and development of cardiovascular diseases.