53356-85-7Relevant academic research and scientific papers
Engaging Alkenes and Alkynes in Deaminative Alkyl-Alkyl and Alkyl-Vinyl Cross-Couplings of Alkylpyridinium Salts
Baker, Kristen M.,Lucas Baca, Diana,Plunkett, Shane,Daneker, Mitchell E.,Watson, Mary P.
, p. 9738 - 9741 (2019/12/02)
An alkyl-alkyl cross-coupling of Katritzky alkylpyridinium salts and organoboranes, formed in situ via hydroboration of alkenes, has been developed. This method utilizes the abundance of both alkyl amine precursors and alkenes to form C(sp3)-C(sp3) bonds. This strategy is also effective with alkynes, enabling a C(sp3)-C(sp2) cross-coupling. Under these mild conditions, a broad range of functional groups, including protic groups, is tolerated. As seen with previous alkylpyridinium cross-couplings, mechanistic studies support an alkyl radical intermediate.
Process for preparing aldehydes
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Page/Page column 6, (2008/06/13)
A process is disclosed for preparing aldehydes by isomerization of the corresponding unsaturated primary alcohols using a transition metal catalyst system, in an alcoholic solvent and in the presence of an acid. An aldehyde forms by isomerizing an unsatur
2-(2,6-DIMETHYLPIPERIDINO)ACETONITRILE AS AN ACYL CARBANION EQUIVALENT
Wakamatsu, Takeshi,Kondo, Junichi,Hobara, Satoshi,Ban, Yoshio
, p. 481 - 484 (2007/10/02)
Reaction of lithio 2-(2,6-dimethylpiperidino)acetonitrile with alkyl halides affords monoalkylation products which are easily hydrolyzed under mild conditions to give the homogeneous aldehyde or its acetal in moderate yield.In the case of alkyl halides having an electron donating group on aromatic ring the cyclization products are obtained.
