53359-46-9Relevant academic research and scientific papers
Starch-sulfuric acid (SSA) as catalyst for a one-pot synthesis of 1,5-diaryl-1H-pyrazoles
Hatamjafari, Farhad
, p. 1560 - 1563 (2013/09/02)
Protocols with starch-sulfuric acid (SSA) as reusable catalyst for the synthesis of aryl-1H-pyrazoles are described. SSA acted as an efficient and environmentally friendly catalyst for the regioselective condensation of Baylis-Hillman adducts 1 with phenylhydrazine hydrochloride leading to the new 1,5-diaryl-1H-pyrazole 2a-2e in excellent yields (Scheme and Table 1). Copyright
Microwave assisted synthesis of arylpyrazoles using montmorillonite K-10
Hatamjafari, Farhad
, p. 2339 - 2340 (2013/05/09)
Montmorillonite K-10 clay catalyzed Friedlander condensation of Baylis-Hillman adducts with phenyl hydrazine hydrochloride afforded 1,5-diarylpyrazoles.
A green, reusable and highly efficient heterogeneous catalyst for the synthesis of arylpyrazoles using nano-Fe2O3
Hatamjafari, Farhad
scheme or table, p. 141 - 143 (2012/08/07)
Series of some new arylpyrazole derivatives have been synthesized in good yields via one-pot condensation reaction using nano-Fe2O3 as heterogeneous catalyst.
Regioselective synthesis of 1,3,4,5-tetrasubstituted pyrazoles from Baylis-Hillman adducts
Lee, Ka Young,Kim, Jeong Mi,Kim, Jae Nyoung
, p. 6737 - 6740 (2007/10/03)
Tetrasubstituted pyrazole derivatives 3a-j were synthesized regioselectively in good yields from the reaction of Baylis-Hillman adducts 1a-f and hydrazine hydrochlorides 2a-d in 1,2-dichloroethane.
Novel 1,5-diphenylpyrazole nonnucleoside HIV-1 reverse transcriptase inhibitors with enhanced activity versus the delavirdine-resistant P236L mutant: Lead identification and SAR of 3- and 4-substituted derivatives
Genin, Michael J.,Biles, Carolyn,Keiser, Barb J.,Poppe, Susan M.,Swaney, Steven M.,Tarpley, W. Gary,Yagi, Yoshihiko,Romero, Donna L.
, p. 1034 - 1040 (2007/10/03)
Through computationally directed broad screening, a novel 1,5- diphenylpyrazole (DPP) class of HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs) has been discovered. Compound 2 (PNU-32945) was found to have good activity versus wild-type (ICs
