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Ethyl 4,5-dioxo-1-phenylpyrrolidine-3-carboxylate is a chemical compound with the molecular formula C12H11NO4. It is a white crystalline solid that is soluble in organic solvents. ethyl 4,5-dioxo-1-phenylpyrrolidine-3-carboxylate is a derivative of pyrrolidine, a heterocyclic organic compound, and features a phenyl group attached to the pyrrolidine ring. The molecule contains two carbonyl groups (C=O) at positions 4 and 5, and a carboxylate group (COO-) at position 3. Ethyl 4,5-dioxo-1-phenylpyrrolidine-3-carboxylate is used as an intermediate in the synthesis of various pharmaceuticals and other organic compounds, particularly in the preparation of certain alkaloids and other nitrogen-containing compounds. Its chemical properties and reactivity make it a valuable building block in organic synthesis, allowing for the creation of a wide range of complex molecules.

5336-49-2

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5336-49-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5336-49-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,3 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5336-49:
(6*5)+(5*3)+(4*3)+(3*6)+(2*4)+(1*9)=92
92 % 10 = 2
So 5336-49-2 is a valid CAS Registry Number.

5336-49-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4,5-dioxo-1-phenylpyrrolidine-3-carboxylate

1.2 Other means of identification

Product number -
Other names 4,5-Dioxo-1-phenyl-pyrrolidin-3-carbonsaeure-aethylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5336-49-2 SDS

5336-49-2Relevant academic research and scientific papers

Squaramide-catalysed asymmetric cascade reactions of 2,3-dioxopyrrolidines with 3-chlorooxindoles

Du, Da-Ming,Wen, Jiang-Bo

, p. 1647 - 1656 (2020)

A highly efficient method for the enantioselective construction of dispirocyclic compounds has been developed by the squaramide-catalysed asymmetric Michael addition/cyclization cascade reaction of 2,3-dioxopyrrolidines with 3-chlorooxindoles. The corresp

Squaramide-catalysed asymmetric Michael addition/cyclization cascade reaction of 4-arylmethylidene-2,3-dioxopyrrolidines with 2-isothiocyanato-1-indanones

Du, Da-Ming,Hou, Xi-Qiang,Wen, Jiang-Bo,Yan, Li

supporting information, p. 7181 - 7185 (2021/08/30)

A highly efficient cinchona alkaloid-derived squaramide catalysed asymmetric Michael/cyclization cascade reaction of 4-arylmethylidene-2,3-dioxopyrrolidines with 2-isothiocyanato-1-indanones was successfully developed. This protocol provides an efficient

Enantioselective Hetero-Diels-Alder Reaction and the Synthesis of Spiropyrrolidone Derivatives

Huang, Yekai,Li, Yanan,Sun, Jianan,Li, Jindong,Zha, Zhenggen,Wang, Zhiyong

, p. 8464 - 8472 (2018/07/21)

An efficient enantioselective hetero-Diels-Alder reaction was developed under catalysis of a chiral copper complex. A variety of spiropyrrolidones, which bear a tetra-substituted carbon stereocenter, can be obtained in good yields with excellent enantioselectivities by virtue of this method. Furthermore, a substrate-dependent reaction pathway was proposed on the basis of the isolated intermediates.

Pyrazolo-pyrrolo-pyrimidine-diones

-

, (2008/06/13)

New pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of formula (I), STR1 where R1, R2, R3, R4 and m are as defined in the specification, e.g., 4-(benzoylmethyl)-6-cyclohexyl-6,7-dihydro-2-phenyl-4H-pyrazolo[1

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