5336-93-6Relevant academic research and scientific papers
Substituted dialkanolamines, sulfur analogs and condensed 1,4-oxazine derivatives thereof in viral disease treatment
-
, (2008/06/13)
Substituted dialkanolamines, oxazine and sulfur analogs thereof, useful in treating shipping fever syndrome in mammals are disclosed having the formula: STR1 wherein: Ar is STR2 Z is oxygen or sulfur; R is selected from hydrogen, loweralkyl or STR3 R1 R2, R3, R4, R5, R6 and R7 are selected from hydrogen or loweralkyl; and STR4 when taken together may form a lowercycloalkyl ring or R5 with --ZR2 when taken together may form a 5-membered saturated oxygen or sulfur containing heterocyclic ring; X is selected from hydrogen, halo, loweralkoxy, loweralkyl, trifluoromethyl or dimethylamino and when X is more than 1, it may be the same radical or different; y is 0, 1 or 2; n is one, or zero and when n is 1, the stereoisomers thereof and when n is zero the dotted line becomes an oxygen-carbon bond forming an oxazine ring and the pharmaceutically acceptable acid addition salts thereof.
