4254-20-0

Basic information

• Product Name: 4,4'-DICHLOROBENZOIN
• Synonyms: 4,4'-DICHLOROBENZOIN;4,4-Dichlorobenzoine;1,2-Bis(4-chlorophenyl)-2-hydroxyethanone;2-Hydroxy-1,2-bis(4-chlorophenyl)ethanone;α-Hydroxy-α-(4-chlorophenyl)-4'-chloroacetophenone
• CAS NO: 4254-20-0
• Molecular Formula: C₁₄H₁₀Cl₂O₂
• Molecular Weight: 281.13
• Mol File: 4254-20-0.mol
• Article Data: 101

Chemical Properties

• Melting Point: 88 °C
• Boiling Point: 439.1°Cat760mmHg
• Flash Point: 219.4°C
• Appearance: /
• Density: 1.379g/cm³
• Vapor Pressure: 1.74E-08mmHg at 25°C
• Refractive Index: 1.625
• PKA: 11.62±0.20(Predicted)
• CAS DataBase Reference: 4,4'-DICHLOROBENZOIN(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DICHLOROBENZOIN(4254-20-0)
• EPA Substance Registry System: 4,4'-DICHLOROBENZOIN(4254-20-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 4254-20-0(Hazardous Substances Data)

Usage

General Description

4,4'-Dichlorobenzoin is a chemical compound that belongs to the benzoin family and is composed of two benzene rings with four chlorine atoms. It is a white crystalline solid that is mainly used as a photoinitiator in the process of photopolymerization. Its ability to absorb ultraviolet light and efficiently initiate the polymerization of various monomers makes it a valuable component in the production of adhesives, coatings, and other polymer-based materials. Additionally, 4,4'-dichlorobenzoin is also used in the formulation of dental materials and as an intermediate in the synthesis of pharmaceuticals and agrochemicals. However, it is important to handle this compound with care as it is considered to be a hazardous substance that can cause irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C14H10Cl2O2/c15-11-5-1-9(2-6-11)13(17)14(18)10-3-7-12(16)8-4-10/h1-8,13,17H

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 60-29-7 diethyl ether 
• 30615-54-4 triphenylmethyl bromide 
• 3457-46-3 4,4'-dichlorobenzil 
• 71-43-2 benzene 
• 2642-81-1 1,1-bis(p-chlorophenyl)ethene 
• 104-53-0 3-phenyl-propionaldehyde 
• 873-76-7 para-Chlorobenzyl alcohol 
• 433-27-2 ethyl trifluoroacetaldehyde hemiacetal 
• 7099-88-9 4-chlorophenylglyoxylic acid 
• 151-50-8 potassium cyanide 
• 37580-81-7 1,2-bis(4-chlorophenyl)-1,2-ethandiol 
• 140-88-5 ethyl acrylate 
• 107-13-1 acrylonitrile 

Downstream Products

• 130235-77-7 4-chloro-benzoic acid 1,2-bis-(4-chloro-phenyl)-2-oxo-ethyl ester 
• 174869-06-8 α-(2-cyano-1-methylethyl)-4,4'-dichlorobenzoin 
• 174869-08-0 α-(3-oxobutyl)-4,4'-dichlorobenzoin 
• 174869-03-5 α-(2-cyanoethyl)-4,4'-dichlorobenzoin 
• 174869-05-7 α-(2-ethoxycarbonylethyl)-4,4'-dichlorobenzoin 
• 74-11-3 para-chlorobenzoic acid 
• 5411-95-0 4-Chloro-α-(4-chlorophenyl)-β-[(2-hydroxyethyl)amino]benzeneethanol, monohydrochloride 
• 130649-65-9 1,2-bis-(4-chloro-phenyl)-2-hydroxy-pent-4-en-1-one 
• 395058-57-8 2,3-bis(4-chloro-phenyl)-6-methylquinoxaline 
• 1356581-93-5 (4-chlorophenyl)((1R,2R)-2-methyl-2-phenylcyclopropyl)methanone 
• 30011-04-2 ethyl 4,5?bis(4?chlorophenyl)?2?methyl?1H?pyrrole?3?carboxylate 
• 1362857-42-8 methyl 4,5?bis(4?chlorophenyl)?2?methyl?1H?pyrrole?3?carboxylate 
• 42456-08-6 1?(4,5?bis(4?chlorophenyl)?2?methyl?1H?pyrrole?3?yl)ethanone 
• 1362857-43-9 1-(4,5-bis(4-chlorophenyl)-2-phenyl-1H-pyrrol-3-yl)ethanone 

Relevant articles and documents

Synthesis, cytotoxic and antibacterial studies of p-benzyl-substituted NHC-silver(I) acetate compounds derived from 4,5-di-p-diisopropylphenyl- or 4,5-di-p-chlorophenyl-1H-imidazole

4,5-Di(p-isopropylphenyl)-1H-imidazole (2a) and 4,5-di(p-chlorophenyl)-1H- imidazole (2b) were prepared from the appropriately substituted benzoin precursors and then reacted with five p-substituted benzyl halide derivatives through N-dibenzylation to the

Synthesis of thiazolium salts and their screening for catalytic activity

A facile synthetic method to prepare thiazolium-based ionic liquids in high yield was developed. The direct alkylation of thiazole was performed using a trialkyl orthoester as both the alkyl donor and the solvent. The synthesized thiazolium salts were sub

N-PEGylated Thiazolium Salt: A Green and Reusable Homogenous Organocatalyst for the Synthesis of Benzoins and Acyloins

N-PEGylated-thiazolium salt is used as efficient catalyst for the benzoin condensation. The catalyst was synthesized by reaction of activated polyethylene glycol 10,000 (PEG-10000) with 4-methyl-5-thiazoleethanol (sulfurol). Reaction mixture undergoes temperature-assisted phase transition and catalyst separated by simple filtration. After reaction course, catalyst can be recycled and reused without any apparent loss of activity which makes this process cost effective and hence ecofriendly. Synthesized benzoins and acyloins by this method have been characterized on the basis of melting point and 1H-NMR spectral studies. Graphic Abstract: [Figure not available: see fulltext.]

Zinc salt-catalyzed reduction of α-aryl imino esters, diketones and phenylacetylenes with water as hydrogen source

The zinc salt-catalyzed reduction of α-aryl imino esters, diketones and phenylacetylenes with water as hydrogen source and zinc as reductant was successfully conducted. The presented method provides a low-cost, environmentally friendly and practical preparation of α-aryl amino esters, α-hydroxyketones and phenylethylenes. By using D2O as deuterium source, the corresponding products were obtained in high efficiency with excellent deuterium incorporation rate, which gives a cheap and safe tool for access to valuable deuterium-labelled compounds. This journal is