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2,3-bis(hydroxymethyl)-1-methylpyrrole, also known as BHMP, is a chemical compound with a molecular formula C7H11NO2. It is a rare central intermediate in the biosynthesis of the actinomycin antibiotics, which are potent antitumor agents. BHMP is characterized by its unique structural properties and high reactivity, making it a valuable building block in the synthesis of complex organic compounds. Its potential as a chemotherapeutic agent has been studied, demonstrating cytotoxic activity against various cancer cell lines and promising anticancer properties.

53365-77-8

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53365-77-8 Usage

Uses

Used in Pharmaceutical Industry:
2,3-bis(hydroxymethyl)-1-methylpyrrole is used as a chemotherapeutic agent for its cytotoxic activity against various cancer cell lines. Its potential as an anticancer compound has been investigated, making it a promising candidate for the development of new cancer treatments.
Used in Organic Synthesis:
2,3-bis(hydroxymethyl)-1-methylpyrrole is used as a valuable building block in the synthesis of complex organic compounds due to its unique structural properties and high reactivity. It can undergo condensation reactions with other molecules, contributing to the creation of novel and biologically active compounds.
Used in Precursor Synthesis:
2,3-bis(hydroxymethyl)-1-methylpyrrole is used as a potential precursor for the synthesis of biologically active compounds. Its promising anticancer properties have led to investigations into its use in the development of new pharmaceuticals and therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 53365-77-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,3,6 and 5 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 53365-77:
(7*5)+(6*3)+(5*3)+(4*6)+(3*5)+(2*7)+(1*7)=128
128 % 10 = 8
So 53365-77-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H11NO2/c1-8-3-2-6(4-9)7(8)5-10/h2-3,9-10H,4-5H2,1H3

53365-77-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [2-(hydroxymethyl)-1-methylpyrrol-3-yl]methanol

1.2 Other means of identification

Product number -
Other names 2,3-Bishydroxymethyl-1-methylpyrrol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53365-77-8 SDS

53365-77-8Relevant academic research and scientific papers

DNA interstrand cross-linking reactions of pyrrole-derived, bifunctional electrophiles: Evidence for a common target site in DNA

Woo, Jinsuk,Sigurdsson, Snorri Th.,Hopkins, Paul B.

, p. 3407 - 3415 (2007/10/02)

The site of DNA interstrand cross-linking identified by a family of pyrrole-derived bifunctional electrophiles was studied in vitro in synthetic DNA duplexes. This family includes reductively activated mitomycin C (1), oxidatively activated pyrrolizidine

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