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(1Z)-2-(biphenyl-4-yl)-N-hydroxy-2-oxoethanimidoyl chloride, commonly referred to as BPCl, is a chemical compound characterized by its molecular formula C14H10ClNO2. As a derivative of biphenyl, BPCl belongs to the class of imidoyl chlorides, which are recognized for their reactivity with various nucleophiles. (1Z)-2-(biphenyl-4-yl)-N-hydroxy-2-oxoethanimidoyl chloride plays a pivotal role as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, and it also serves as a building block for the preparation of other organic molecules. BPCl's significance extends to medicinal chemistry and as a reagent in organic synthesis, establishing its importance in the realm of chemical research and development.

5337-28-0

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5337-28-0 Usage

Uses

Used in Organic Synthesis:
BPCl is utilized as a reactive intermediate in the field of organic synthesis for the creation of a variety of complex organic molecules. Its reactivity with nucleophiles makes it a valuable component in the formation of new chemical bonds and the synthesis of target compounds.
Used in Pharmaceutical and Agrochemical Industries:
As a key intermediate, BPCl is instrumental in the development and synthesis of pharmaceuticals and agrochemicals. Its role in these industries is crucial for the production of various drugs and agricultural chemicals that are designed to treat or prevent diseases and pests, respectively.
Used in Medicinal Chemistry:
BPCl's potential applications in medicinal chemistry are significant, as it can be used to develop new drugs with specific therapeutic properties. Its reactivity allows for the exploration of novel chemical structures that may lead to the discovery of more effective treatments for various diseases.
Used in Research and Development:
In the field of chemical research and development, BPCl serves as an important chemical for experimentation and innovation. Its unique properties and reactivity contribute to the advancement of knowledge in organic chemistry and the development of new methodologies and techniques for synthesizing complex molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 5337-28-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,3 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5337-28:
(6*5)+(5*3)+(4*3)+(3*7)+(2*2)+(1*8)=90
90 % 10 = 0
So 5337-28-0 is a valid CAS Registry Number.

5337-28-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (1Z)-N-hydroxy-2-oxo-2-(4-phenylphenyl)ethanimidoyl chloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:5337-28-0 SDS

5337-28-0Upstream product

5337-28-0Relevant academic research and scientific papers

Synthesis of (2-hydroxo-5-chlorophenylaminoisonitrosoacetyl)phenyl ligands and their complexes: Spectral, thermal and solvent-extraction studies

Karipcin, Fatma,Dede, Bülent,Cengiz, Mustafa

body text, p. 530 - 540 (2010/08/04)

Four different types of new ligands Ar[COC(NOH)R] n (Ar=biphenyl, n = 1 H2L1; Ar=biphenyl, n = 2 H 4L2; Ar=diphenylmethane, n = 1 H2L3; Ar=diphenylmethane, n = 2 H4L4; R=2-amino-4-chlorophenol in all ligands) have been obtained from 1 equivalent of chloroketooximes Ar[COC(NOH)Cl] n (HL1-H2L4) and 1 equivalent of 2-amino-4-chlorophenol (for H2L1 and H 2L3) or 2 equivalent of 2-amino-4-chlorophenol (for H 4L2 and H4L4). (Mononuclear or binuclear cobalt(II), nickel(II), copper(II) and zinc(II) complexes were synthesized with these ligands.) These compounds have been characterized by elemental analyses, AAS, infra-red spectra and magnetic susceptibility measurements. The ligands have been further characterized by 1H NMR. The results suggest that the dinuclear complexes of H2L1 and H2L3 have a metal:ligand ratio of 1:2; the mononuclear complexes of H4L2 and H4L4 have a metal:ligand ratio of 1:1 and dinuclear complexes H4L2 and H4L4 have a metal:ligand ratio of 2:1. The binding properties of the ligands towards selected transition metal ions (Mn II, CoII, NiII, CuII, Zn II, PbII, CdII, HgII) have been established by extraction experiments. The ligands show strong binding ability towards mercury(II) ion. In addition, the thermal decomposition of some complexes is studied in nitrogen atmosphere.

Synthesis and characterization of some Borylated (4-Biphenyl)(N-arylamino) glyoxime complexes

Karipcin,Erdem-Tuncmen,Baskale-Akdogan,Dede

body text, p. 525 - 535 (2010/02/28)

A series of Cu(II), Ni(II) and Co(III) complexes of the type [M(L n)2(H2O)2(BF2) 2] and [Co(Ln)2PyCl(BF2) 2] (where M = Cu(II) or Ni(II); n = 1,2; L = bidentate dioxime ligands) have been synthesized by the reactions of dioxime complexes with boron trifluoride diethyl ether complex in acetonitrile under nitrogen atmosphere. In all these reactions, the bridging protons of the dioxime complexes replace BF2 groups. These complexes have been characterized by elemental analyses, FT-IR, ICP-OES, 1H NMR together with magnetic susceptibility measurements. In particular, the thermal decomposition of all the complexes was studied in nitrogen atmosphere.

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