5340-48-7

Usage

Uses

Used in Pharmaceutical Industry:
2,2-dipropylvaleronitrile is used as an impurity in the production of Valproic Acid (V094750) for its antiepileptic and anticonvulsant properties. It plays a role in stabilizing the mood of patients with bipolar disorder by modulating the levels of certain neurotransmitters in the brain.
Additionally, as an impurity, it may be subject to regulatory controls and quality assurance measures to ensure the safety and efficacy of the final pharmaceutical product. The presence of 2,2-dipropylvaleronitrile in Valproic Acid could also be a subject of interest for researchers looking to understand its potential effects on the drug's overall performance and patient outcomes.

InChI:InChI=1/C11H21N/c1-4-7-11(10-12,8-5-2)9-6-3/h4-9H2,1-3H3

Upstream product

• 106-94-5 propyl bromide 
• 75-05-8 acetonitrile 
• 110-59-8 pentanonitrile 
• 13310-75-3 di-N-propyl acetonitrile 

Downstream Products

• 52061-73-1 2,2-di-n-propyl-valeramide 
• 80606-17-3 3,3-Dipropyl-2-hexanonoxim-pikrat 
• 13310-75-3 di-N-propyl acetonitrile 
• 52061-75-3 2,2-dipropyl-valeric acid 

Relevant academic research and scientific papers

Deprotonation-alkylation of alkyl cyanides under sonochemical conditions

Deprotonation-alkylation of n-alkyl cyanides can be readily effected by an alkyl halide in the presence of sodium in a one pot procedure. Yields are generally better than in the usual methods, and the overall reaction conditions have important advantages

Process for introducing alkyl radicals into carbon chains having a functional group and compounds prepared by said process

Process for introducing a substituent selected from branched- or straight-chain alkyl radicals having from 1 to 12 carbon atoms, aralkyl or cycloalkyl radicals in which the alkyl moiety has from 1 to 4 carbon atoms, into a carbon chain bearing a stable functional group the said carbon chain having at least one proton in α-position in relation to this functional group, process whereby, in a first step, this carbon chain is reacted with a complex base comprising a mixture of alkali metal amide and alkali metal alcoholate suspended in an anhydrous organic solvent to provide temporarily a carbanion, then in a second step this carbanion is reacted in an anhydrous organic solvent with an alkyl, aralkyl or cycloalkyl halide corresponding to the substituent to be introduced.

Wanderungstendenzen cyclischer, polycyclischer und methylverzweigter Alkylreste bei der Beckmann-Umlagerung

The migration aptitudes of polycyclic bridgehead groups, cycloalkyl groups as well as of β-, γ- and δ-branched alkyl groups in the Chapman variant of the Beckmann rearrangement were determined.From these data it is concluded that at transition state 2 the migrating group is not resembling a planarised carbenium ion R+, but rather a pentacoordinated carbonium ion structure.Because only small geometrical changes occur in the migrating group vertical stabilisation of charge at transition state is believed to have significant influence on the migration aptitudes.