53427-79-5

Basic information

• Product Name: 2(1H)-Pyridinone, 5-methyl-1-[3-(trifluoromethyl)phenyl]-
• CAS NO: 53427-79-5
• Molecular Formula: C13H10F3NO
• Molecular Weight: 253.224
• Mol File: 53427-79-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2(1H)-Pyridinone, 5-methyl-1-[3-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyridinone, 5-methyl-1-[3-(trifluoromethyl)phenyl]-(53427-79-5)
• EPA Substance Registry System: 2(1H)-Pyridinone, 5-methyl-1-[3-(trifluoromethyl)phenyl]-(53427-79-5)

Safety Data

• Hazardous Substances Data: 53427-79-5(Hazardous Substances Data)

Upstream product

• 1003-68-5 5-methyl-2-pyridone 
• 401-78-5 3-bromo-1-trifluoromethylbenzene 
• 7681-65-4 copper(I) iodide 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 374072-42-1 2-chloro-5-methyl-1-(3-trifluoromethyl-phenyl)-pyridinium chloride 
• 374072-40-9 5-methyl-1-(3-trifluoromethyl-phenyl)-2(1H)-pyridinethione 

Relevant articles and documents

COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS

Disclosed are compounds and methods for treating inflammatory and fibrotic disorders, including methods of modulating a stress activated protein kinase (SAPK) system with an active compound, wherein the active compound exhibits low potency for inhibition of the p38 MAPK; and wherein the contacting is conducted at a SAPK-modulating concentration that is at a low percentage inhibitory concentration for inhibition of the p38 MAPK by the compound. Also disclosed are derivatives and analogs of pirfenidone, useful for modulating a stress activated protein kinase (SAPK) system.

Substituted iminoazines

The invention relates to novel substituted iminoazines of the general formula (I) in which R1, R2, R3, R4, Z1, Z2 and Z3 are each as defined in the description, to a plurality of processes and intermediates for their preparation and to their use as herbicides.

Treatment of cytokine growth factor caused disorders

In preferred embodiments, a method of prevention and treatment of disorders caused by enhanced proliferation and enhanced biosynthesis caused by cytokine growth factors in humans and other animals, the method including: administering to a human or other animal an effective dose of a pharmaceutical substance including an N-substituted 2(1H) pyridone and/or an N-substituted 3(1H) pyridone; and a composition for prevention and treatment of disorders caused by enhanced proliferation and enhanced biosynthesis caused by cytokine growth factors in humans and other animals, the composition including: a pharmaceutical preparation including an effective dose of an N-substituted 2(1H) pyridone and/or an N-substituted 3(1H) pyridone.